Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.74 |
| ▸ | GAA | P10253 | 1/20 | 0.74 |
| ▸ | GRN | P28799 | 1/20 | 0.55 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | RPA1 | P27694 | 1/20 | 0.43 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.42 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.42 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31125205 | 0.88 | ALDH1A1 (0.57) | ALDH1A1GAAGRNSORT1KDM4E | |
| SCHEMBL4498910 | 0.85 | ALDH1A1 (1.00) | ALDH1A1GAAGRNSORT1KDM4E | |
| SCHEMBL19994228 | 0.81 | LMNA (0.55) | ALDH1A1GAAKDM4ERECQLKMT2A | |
| SCHEMBL6414804 | 0.80 | ALDH1A1 (0.73) | ALDH1A1GAAGRNSORT1KDM4E | |
| SCHEMBL68764 | 0.76 | RPA1 (0.65) | ALDH1A1GAAGRNSORT1KDM4E | |
| SCHEMBL5402973 | 0.76 | ALDH1A1 (0.63) | ALDH1A1GAAGRNSORT1KDM4E | |
| SCHEMBL4422536 | 0.75 | ALDH1A1 (0.75) | ALDH1A1GAAGRNSORT1KDM4E | |
| SCHEMBL2927650 | 0.75 | ALDH1A1 (0.74) | ALDH1A1GAAGRNSORT1KDM4E | |
| SCHEMBL30070407 | 0.75 | ALDH1A1 (0.44) | ALDH1A1GAAKDM4EPTGS2SMN1; SMN2 | |
| SCHEMBL4993401 | 0.75 | ALDH1A1 (0.61) | ALDH1A1GAAGRNSORT1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109689629-B | Process for preparing 3-fluoroalkyl-5-pyrazole carboxylic acid esters and 3-fluoroalkyl-5-pyrazole carboxylic acids | 拜耳作物科学股份公司 | 2022-11-29 | — | — | CN | disclosed |
| EP-3515893-B1 | PROCESS FOR PREPARING 3-FLUOROALKYL-5-PYRAZOLECARBOXYLATES AND 3-FLUOROALKYL-5-PYRAZOLECARBOXYLIC ACIDS | BAYER CROPSCIENCE AG (DE) | 2020-10-21 | — | — | EP | disclosed |
| US-10556867-B2 | Process for preparing 3-fluoroalkyl-5-pyrazolecarboxylates and 3-fluoroalkyl-5-pyrazolecarboxylic acids | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-02-11 | — | — | US | disclosed |
| US-10556867-B2 | Process for preparing 3-fluoroalkyl-5-pyrazolecarboxylates and 3-fluoroalkyl-5-pyrazolecarboxylic acids | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-02-11 | — | — | US | disclosed |
| EP-3515893-A1 | PROCESS FOR PREPARING 3-FLUOROALKYL-5-PYRAZOLECARBOXYLATES AND 3-FLUOROALKYL-5-PYRAZOLECARBOXYLIC ACIDS | Bayer CropScience Aktiengesellschaft (DE) | 2019-07-31 | — | — | EP | disclosed |
| US-20190225586-A1 | PROCESS FOR PREPARING 3-FLUOROALKYL-5-PYRAZOLECARBOXYLATES AND 3-FLUOROALKYL-5-PYRAZOLECARBOXYLIC ACIDS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-07-25 | — | — | US | disclosed |
| US-20190225586-A1 | PROCESS FOR PREPARING 3-FLUOROALKYL-5-PYRAZOLECARBOXYLATES AND 3-FLUOROALKYL-5-PYRAZOLECARBOXYLIC ACIDS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-07-25 | — | — | US | disclosed |
| CN-109689629-A | The method for preparing 3- fluoroalkyl -5- pyrazole carboxylate and 3- fluoroalkyl -5- pyrazole carboxylic acid | 拜耳作物科学股份公司 | 2019-04-26 | — | — | CN | disclosed |
| WO-2018054807-A1 | PROCESS FOR PREPARING 3-FLUOROALKYL-5-PYRAZOLECARBOXYLATES AND 3-FLUOROALKYL-5-PYRAZOLECARBOXYLIC ACIDS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-03-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190225586-A1 | PROCESS FOR PREPARING 3-FLUOROALKYL-5-PYRAZOLECARBOXYLATES AND 3-FLUOROALKYL-5-PYRAZOLECARBOXYLIC ACIDS | KYAT3, PFKFB3, PFKFB1 | ALDH1A1 1023/4885GAA 2273/4885GRN 2469/4885 |
| US-10556867-B2 | Process for preparing 3-fluoroalkyl-5-pyrazolecarboxylates and 3-fluoroalkyl-5-pyrazolecarboxylic acids | KYAT3, PFKFB3, PFKFB1 | ALDH1A1 1023/4885GAA 2273/4885GRN 2469/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.