Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2957517 | 0.91 | MAPT (0.43) | HSD17B10TSHRMAPTGRM5GAA | |
| SCHEMBL6427112 | 0.89 | HSD17B10 (0.35) | HSD17B10TSHRMAPTGRM5GAA | |
| SCHEMBL6409570 | 0.85 | MAOB (0.38) | HSD17B10TSHRMAPTGRM5GAA | |
| SCHEMBL4177681 | 0.82 | L3MBTL1 (0.40) | TSHRMAPTGAAL3MBTL1DPP4 | |
| SCHEMBL5719564 | 0.82 | TSHR (0.38) | HSD17B10TSHRMAPTGRM5GAA | |
| SCHEMBL5719583 | 0.80 | ACHE (0.38) | GAAL3MBTL1MEN1KMT2ALMNA | |
| SCHEMBL6422392 | 0.78 | — | — | |
| SCHEMBL2959131 | 0.77 | CNR1 (0.41) | HSD17B10TSHRMAPTGAAL3MBTL1 | |
| SCHEMBL2954897 | 0.76 | GAA (0.44) | HSD17B10TSHRMAPTGAAL3MBTL1 | |
| SCHEMBL5718918 | 0.74 | CNR1 (0.38) | HSD17B10TSHRMAPTGAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1514552-A1 | NOVEL FUSED IMIDAZOLE DERIVATIVE | Eisai Co., Ltd. (JP) | 2005-03-16 | — | — | EP | disclosed |