SCHEMBL641493

SCHEMBL641493

CCCCCC=C(CCCCC)CCCCC

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EP300 Q09472 1/20 0.46
PPARG P37231 4/20 0.45
PPARD Q03181 4/20 0.45
PPARA Q07869 4/20 0.45
TERT O14746 3/20 0.45
PTPN1 P18031 3/20 0.45
CYP1A2 P05177 2/20 0.45
MAPT P10636 2/20 0.45
CYP2C19 P33261 2/20 0.45
BLM P54132 2/20 0.45
HSD17B10 Q99714 2/20 0.45
FABP4 P15090 2/20 0.45
FAAH O00519 2/20 0.45
KMT2A Q03164 2/20 0.45
F7 P08709 2/20 0.45
F3 P13726 2/20 0.45
PTGS1 P23219 2/20 0.45
GMNN O75496 1/20 0.45
USP2 O75604 1/20 0.45
LMNA P02545 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11055241 0.97 EP300 (0.50) EP300PPARGPPARDPPARATERT
SCHEMBL27603791 0.97 EP300 (0.50) EP300PPARGPPARDPPARATERT
SCHEMBL11789494 0.97 EP300 (0.50) EP300PPARGPPARDPPARATERT
SCHEMBL11055246 0.97 EP300 (0.50) EP300PPARGPPARDPPARATERT
SCHEMBL11789217 0.97 EP300 (0.50) EP300PPARGPPARDPPARATERT
SCHEMBL11790163 0.97 EP300 (0.50) EP300PPARGPPARDPPARATERT
SCHEMBL9230921 0.95 CES2 (0.42) EP300PPARGPPARDPPARATERT
SCHEMBL28049343 0.93 EP300 (0.47) EP300PPARGPPARDPPARATERT
SCHEMBL11787341 0.93 EP300 (0.47) EP300PPARGPPARDPPARATERT
SCHEMBL28049405 0.93 EP300 (0.47) EP300PPARGPPARDPPARATERT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 184 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112552897-B Triaryl vinyl photochromic material, method and application thereof as 3D printing ink 西北工业大学 2024-05-28 CN claimed
CN-117865933-A Stilbene photochromic material containing dibenzothiophene and preparation method thereof 上海陕煤高新技术研究院有限公司 2024-04-12 CN claimed
CN-117865917-A Photochromic aggregation-state-dependent triarylethylene material and preparation method thereof 上海陕煤高新技术研究院有限公司 2024-04-12 CN claimed
CN-116789518-A 2-position phenyl substituted triarylethylene photochromic material and preparation method and application thereof 西北工业大学 2023-09-22 CN claimed
CN-116283746-A Pyridine derivative-containing triarylethylene photochromic material and preparation and application methods thereof 西北工业大学 2023-06-23 CN claimed
CN-113818034-B Electrochemical synthesis method of 2-aryl-1,2-diphenylethanone 淮阴工学院 2023-03-21 CN claimed
CN-113818034-A Electrochemical synthesis method of 2-aryl-1, 2-diphenylethanone 淮阴工学院 2021-12-21 CN claimed
CN-108623543-A The class photochromic material of triaryl-ethylene containing furan derivatives and its synthetic method and application 中山大学 2018-10-09 CN claimed
CN-107522688-A The class photochromic material of triaryl-ethylene containing thiophene derivant and its synthetic method and application 中山大学 2017-12-29 CN claimed
CN-107245148-A Porous supermolecule organic framework material of novel three-dimensional and its preparation method and application 中山大学 2017-10-13 CN claimed
CN-201527998-U Plant growth light source based on OLED UNIV SHANGHAI 2010-07-14 CN claimed
CN-101662001-A OLED-based plant growth light source and preparation method thereof UNIV SHANGHAI 2010-03-03 CN claimed
CN-1086576-C Hypoglycemic agents LILLY CO ELI (US) 2002-06-26 CN claimed
US-20010051636-A1 Combination treatment for inhibiting bone loss BLACK LARRY J (US) 2001-12-13 US claimed
EP-0693285-A2 Pharmaceutical compositions containing a bisphosphonate and an anti-resorptive agent for inhibiting bone loss ELI LILLY AND COMPANY (US) 1996-01-24 EP claimed
CN-1100933-A Hypoglycemic agents LILLY CO ELI (US) 1995-04-05 CN claimed
EP-0635264-A2 Antiestrogens as hypoglycemic agents ELI LILLY AND COMPANY (US) 1995-01-25 EP claimed
JP-4330043-A None JP disclosed
EP-0470310-A1 Novel benzopyrans and process for their production Council of Scientific and Industrial Research (IN) 1992-02-12 EP disclosed
US-4879315-A Cyclopropyl analogs as anti-estrogenic, anti-tumor and female fertility agents THE BOARD OF REGENTS FOR THE UNIVERSITY OF OKLAHOMA (US) 1989-11-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010051636-A1 Combination treatment for inhibiting bone loss SOST, BMP2, PTH1R EP300 1112/4885PPARG 130/4885PPARD 163/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.