SCHEMBL6415153

SCHEMBL6415153

C/C=C(/C(=O)O)c1ccccc1COc1ncccc1C

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.41
SGMS2 Q8NHU3 1/20 0.40
HTT P42858 3/20 0.39
NPSR1 Q6W5P4 2/20 0.39
KMT2A Q03164 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
CNR2 P34972 3/20 0.38
ALDH1A1 P00352 2/20 0.38
CNR1 P21554 2/20 0.38
LMNA P02545 1/20 0.37
KDM4E B2RXH2 1/20 0.37
POLB P06746 1/20 0.37
MAPK8 P45983 1/20 0.37
CTNNB1 P35222 1/20 0.36
WNT3A P56704 1/20 0.36
TP53 P04637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8338962 1.00 L3MBTL1 (0.41) L3MBTL1SGMS2HTTNPSR1KMT2A
SCHEMBL8338953 0.89 TDP1 (0.39) L3MBTL1SGMS2HTTNPSR1KMT2A
SCHEMBL29355966 0.89 TDP1 (0.39) L3MBTL1SGMS2HTTNPSR1KMT2A
SCHEMBL6415145 0.89 TDP1 (0.39) L3MBTL1SGMS2HTTNPSR1KMT2A
SCHEMBL6415157 0.89 TDP1 (0.39) L3MBTL1SGMS2HTTNPSR1KMT2A
SCHEMBL8314159 0.82 L3MBTL1 (0.41) L3MBTL1SGMS2HTTNPSR1KMT2A
SCHEMBL29709962 0.81 SGMS2 (0.40) L3MBTL1SGMS2HTTNPSR1KMT2A
SCHEMBL5688372 0.81 SGMS2 (0.40) L3MBTL1SGMS2HTTNPSR1KMT2A
SCHEMBL8724339 0.81 GABRA5 (0.40) HTTKMT2AALDH1A1TP53
SCHEMBL8546624 0.80 TDP1 (0.41) L3MBTL1SGMS2HTTNPSR1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240041028-A1 DELIVERY SYSTEM FOR PLANT PROTECTION OMYA INTERNATIONAL AG (CH) 2024-02-08 US disclosed
EP-3244732-B1 USE OF SURFACE-REACTED CALCIUM CARBONATE AS CARRIER FOR AGROCHEMICAL COMPOUNDS OMYA INT AG (CH) 2023-05-03 EP disclosed
US-11566140-B2 Exterior coating composition TROY CORPORATION (US) 2023-01-31 US disclosed
US-20200377738-A1 EXTERIOR COATING COMPOSITION TROY CORPORATION (US) 2020-12-03 US disclosed
WO-2020243293-A1 EXTERIOR COATING COMPOSITION TROY CORPORATION (US) 2020-12-03 WO disclosed
US-10292383-B2 Use of surface-reacted calcium carbonate as carrier for agrochemical compounds OMYA INTERNATIONAL AG (CH) 2019-05-21 US disclosed
US-20180014532-A1 USE OF SURFACE-REACTED CALCIUM CARBONATE AS CARRIER FOR AGROCHEMICAL COMPOUNDS OMYA INTERNATIONAL AG (CH) 2018-01-18 US disclosed
EP-3244732-A1 USE OF SURFACE-REACTED CALCIUM CARBONATE AS CARRIER FOR AGROCHEMICAL COMPOUNDS Omya International AG (CH) 2017-11-22 EP disclosed
WO-2016113289-A1 USE OF SURFACE-REACTED CALCIUM CARBONATE AS CARRIER FOR AGROCHEMICAL COMPOUNDS OMYA INTERNATIONAL AG (CH) 2016-07-21 WO disclosed
EP-3045042-A1 USE OF SURFACE-REACTED CALCIUM CARBONATE AS CARRIER FOR AGROCHEMICAL COMPOUNDS Omya International AG (CH) 2016-07-20 EP disclosed
US-8841294-B2 Active ingredient combinations having insecticidal and acaricidal properties BAYER CROPSCIENCE AG (DE) 2014-09-23 US disclosed
US-20050187215-A1 synergistic mixture of certain previously disclosed cyclic ketoenols and agonists or antagonists of nicotinic acetylcholine receptors BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2005-08-25 US disclosed
US-6893651-B1 Synergistic combination of cyclic ketoenol with agonists or antagonists of nicotinic acetylcholine receptors; protecting plants BAYER AKTIENGESELLSCHAFT (DE) 2005-05-17 US disclosed
US-6846777-B2 Synergistic biocidal composition THOR GMBH (DE) 2005-01-25 US disclosed
US-20030199490-A1 Synergistic biocidal composition THOR GMBH (DE) 2003-10-23 US disclosed
US-5972971-A WOOD PRESERVATIVE CONSISTS OF A MIXTURE OF METACONAZOLE OR AN ACID ADDITION SALT OR METAL COMPLEX AND IMIDACLOPRID OR SALT OR METAL COMPLEX BAYER AKTIENGESELLSCHAFT (DE) 1999-10-26 US disclosed
US-5466693-A FOE USE IN THE CULTIVATION OF RICE IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1995-11-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050187215-A1 synergistic mixture of certain previously disclosed cyclic ketoenols and agonists or antagonists of nicotinic acetylcholine receptors CHRNG, CHRM3, CHRNE L3MBTL1 2322/4885SGMS2 1090/4885HTT 4347/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.