Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 4/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | APEX1 | P27695 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | STAT6 | P42226 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6159705 | 0.81 | CYP1A2 (0.52) | CYP1A2CYP2D6L3MBTL1CYP3A4CYP2C19 | |
| SCHEMBL6415916 | 0.76 | ALDH1A1 (0.44) | CYP1A2L3MBTL1CYP2C19ALDH1A1SMN1; SMN2 | |
| SCHEMBL28996772 | 0.74 | APEX1 (0.59) | CYP1A2CYP2D6L3MBTL1CYP3A4CYP2C19 | |
| SCHEMBL28996770 | 0.74 | APEX1 (0.59) | CYP1A2CYP2D6L3MBTL1CYP3A4CYP2C19 | |
| SCHEMBL30429401 | 0.74 | APEX1 (0.59) | CYP1A2CYP2D6L3MBTL1CYP3A4CYP2C19 | |
| SCHEMBL28069624 | 0.72 | ALDH1A1 (0.49) | CYP1A2CYP2D6L3MBTL1CYP3A4CYP2C19 | |
| SCHEMBL10989220 | 0.71 | CYP1A2 (0.67) | CYP1A2CYP2D6L3MBTL1CYP3A4CYP2C19 | |
| SCHEMBL29023728 | 0.70 | CYP1A2 (0.56) | CYP1A2CYP2D6L3MBTL1CYP3A4CYP2C19 | |
| SCHEMBL10037466 | 0.69 | APEX1 (0.64) | CYP1A2CYP2D6L3MBTL1CYP3A4CYP2C19 | |
| SCHEMBL3022326 | 0.69 | CYP1A2 (0.63) | CYP1A2CYP2D6L3MBTL1CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050119241-A1 | Preparation of 24 alkyl analogs of cholecalciferol and non-racemic compounds | INSTYTUT FARMACEUTYCZNY (PL) | 2005-06-02 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050119241-A1 | Preparation of 24 alkyl analogs of cholecalciferol and non-racemic compounds | CYP24A1, CYP2R1, VDR | CYP1A2 159/4885CYP2D6 83/4885L3MBTL1 2615/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.