Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.32 |
| ▸ | MPL | P40238 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 4/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | SGK1 | O00141 | 1/20 | 0.31 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9485617 | 0.89 | PIK3CG (0.32) | EPHX2MPLCYP2D6MEN1KMT2A | |
| SCHEMBL20573229 | 0.88 | EPHX2 (0.38) | EPHX2MPLCYP2D6MEN1KMT2A | |
| SCHEMBL3389669 | 0.88 | EPHX2 (0.40) | EPHX2MEN1KMT2AGAALMNA | |
| SCHEMBL5802385 | 0.87 | EPHX2 (0.42) | EPHX2MEN1KMT2AGAAHTT | |
| SCHEMBL23387579 | 0.86 | MRGPRX1 (0.33) | EPHX2MPLCYP2D6MEN1KMT2A | |
| SCHEMBL8945001 | 0.86 | CYP2C9 (0.35) | EPHX2MPLCYP2D6MEN1KMT2A | |
| SCHEMBL7526268 | 0.86 | CYP2C9 (0.35) | EPHX2MPLCYP2D6MEN1KMT2A | |
| SCHEMBL20300565 | 0.85 | LMNA (0.33) | EPHX2MPLCYP2D6MEN1KMT2A | |
| SCHEMBL25434904 | 0.85 | TSHR (0.34) | AKR1C3EPHX2MEN1KMT2AALDH1A1 | |
| SCHEMBL963562 | 0.84 | NPC1 (0.42) | EPHX2ALDH1A1LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050033044-A1 | Methods for preparing 2-alkynyladenosine derivatives | BRISTOL-MYERS SQUIBB PHARMA COMPANY | 2005-02-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050033044-A1 | Methods for preparing 2-alkynyladenosine derivatives | ADORA2A, ADORA3, ADORA1 | AKR1C3 171/4885EPHX2 350/4885MPL 4590/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.