Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 4/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | MMP2 | P08253 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8515103 | 0.85 | KDM4E (0.49) | KDM4EMAPK1HDAC1NAMPT | |
| SCHEMBL8513622 | 0.83 | KDM4E (0.58) | KDM4ENAMPT | |
| SCHEMBL8515153 | 0.81 | KDM4E (0.58) | KDM4ENAMPT | |
| SCHEMBL8516388 | 0.81 | KDM4E (0.58) | KDM4ENAMPT | |
| Acetone SCHEMBL28835039 | 0.78 | KDM4E (0.50) | ALDH1A1KDM4ENAMPT | |
| SCHEMBL13349296 | 0.77 | POLB (0.50) | KDM4EMAPK1HDAC1NAMPT | |
| SCHEMBL31365939 | 0.76 | L3MBTL1 (0.57) | ALDH1A1CA2KDM4EMEN1KMT2A | |
| SCHEMBL8031999 | 0.75 | MAPK1 (0.64) | ALDH1A1CA2KDM4EMAPK1CA1 | |
| SCHEMBL16688446 | 0.74 | MAPK1 (0.61) | ALDH1A1CA2KDM4EMAPK1CA1 | |
| SCHEMBL12364920 | 0.73 | EPHX2 (0.60) | CA2KDM4ENAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6897209-B2 | Labelled factor XIIIa substrates | GE HEALTHCARE LIMITED (GB) | 2005-05-24 | — | — | US | disclosed |
| EP-0994730-B1 | LABELLED FACTOR XIIIa SUBSTRATES | AMERSHAM PLC (GB) | 2005-05-04 | — | — | EP | disclosed |
| US-20040076580-A1 | Labelled factor XIIIa substrates | AMERSHAM PLC (GB) | 2004-04-22 | — | — | US | disclosed |
| US-6653299-B1 | Radiotagged complexes; thrombosis, embolism, atherosclerosis, inflammation, cancer | NYCOMED AMERSHAM PLC (GB) | 2003-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040076580-A1 | Labelled factor XIIIa substrates | F13B, F7, F9 | ALDH1A1 4469/4885NPSR1 3483/4885CA2 2989/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.