Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RRM1 | P23921 | 1/20 | 0.49 |
| ▸ | RRM2 | P31350 | 1/20 | 0.49 |
| ▸ | RRM2B | Q7LG56 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 8/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.46 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6431153 | 0.91 | MAPT (0.47) | RRM1RRM2RRM2BGAAMAPT | |
| SCHEMBL6431849 | 0.88 | RAB9A (0.49) | GAAMAPTSMN1; SMN2RAB9ATP53 | |
| SCHEMBL6431437 | 0.87 | MEN1 (0.50) | GAAMAPTSMN1; SMN2RAB9ATP53 | |
| SCHEMBL6469778 | 0.87 | DDX3X (0.46) | GAAMAPTSMN1; SMN2RAB9ATP53 | |
| SCHEMBL6432172 | 0.86 | GAA (0.47) | GAAMAPTSMN1; SMN2RAB9ATP53 | |
| SCHEMBL6418326 | 0.85 | GAA (0.47) | GAAMAPTSMN1; SMN2RAB9ATP53 | |
| SCHEMBL6418357 | 0.84 | MAPT (0.47) | GAAMAPTSMN1; SMN2RAB9ATP53 | |
| SCHEMBL6470009 | 0.84 | DDX3X (0.55) | GAAMAPTSMN1; SMN2RAB9ATP53 | |
| SCHEMBL6431993 | 0.81 | SMN1; SMN2 (0.51) | GAAMAPTSMN1; SMN2RAB9ATP53 | |
| SCHEMBL6431990 | 0.81 | SMN1; SMN2 (0.51) | GAAMAPTSMN1; SMN2RAB9ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050143382-A1 | Heterocyclic compounds as pharmaceutically active compounds | 4SC AG (DE) | 2005-06-30 | — | — | US | disclosed |
| WO-2005044270-A1 | OXADIAZOLOPYRAZINE DERIVATIVES AS PHARMACEUTICALLY ACTIVE COMPOUNDS | 4SC AG (DE) | 2005-05-19 | — | — | WO | disclosed |
| EP-1529531-A1 | Oxadiazolopyrazine derivatives as pharmaceutically active compounds | 4SC AG (DE) | 2005-05-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050143382-A1 | Heterocyclic compounds as pharmaceutically active compounds | NR5A2, NR1H2, NR2C2 | RRM1 595/4885RRM2 202/4885RRM2B 246/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.