Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 11/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | DDX3X | O00571 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 11/20 | 0.48 |
| ▸ | MAPT | P10636 | 10/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.47 |
| ▸ | HTT | P42858 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6470009 | 0.90 | DDX3X (0.55) | MEN1KMT2ANPC1DDX3XGAA | |
| SCHEMBL6436116 | 0.90 | FADS1 (0.44) | MEN1KMT2ANPC1DDX3XGAA | |
| SCHEMBL6436122 | 0.90 | FADS1 (0.44) | MEN1KMT2ANPC1DDX3XGAA | |
| SCHEMBL6414918 | 0.89 | DDX3X (0.63) | MEN1KMT2ANPC1DDX3XGAA | |
| SCHEMBL6418357 | 0.88 | MAPT (0.47) | MEN1KMT2ANPC1DDX3XGAA | |
| SCHEMBL6416491 | 0.87 | MEN1 (0.49) | MEN1KMT2ANPC1DDX3XGAA | |
| SCHEMBL6418252 | 0.87 | RRM1 (0.49) | MEN1KMT2ANPC1DDX3XGAA | |
| SCHEMBL6440416 | 0.86 | MEN1 (0.47) | MEN1KMT2ANPC1DDX3XGAA | |
| SCHEMBL6431153 | 0.86 | MAPT (0.47) | MEN1KMT2ANPC1GAAMAPT | |
| SCHEMBL6417232 | 0.82 | DDX3X (0.49) | MEN1KMT2ANPC1DDX3XGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050143382-A1 | Heterocyclic compounds as pharmaceutically active compounds | 4SC AG (DE) | 2005-06-30 | — | — | US | disclosed |
| WO-2005044270-A1 | OXADIAZOLOPYRAZINE DERIVATIVES AS PHARMACEUTICALLY ACTIVE COMPOUNDS | 4SC AG (DE) | 2005-05-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050143382-A1 | Heterocyclic compounds as pharmaceutically active compounds | NR5A2, NR1H2, NR2C2 | MEN1 4392/4885KMT2A 3640/4885NPC1 2027/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.