Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6410966 | 0.89 | ALDH1A1 (0.41) | SLC6A4ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL6417559 | 0.86 | HTR1A (0.54) | SLC6A4MEN1KMT2AHTR1AHSD17B10 | |
| SCHEMBL6411526 | 0.85 | HTR1A (0.49) | SLC6A4MEN1KMT2AHTR1A | |
| SCHEMBL6413303 | 0.84 | SLC6A4 (0.50) | SLC6A4ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL6413033 | 0.83 | HTR7 (0.43) | SLC6A4HTR1ADRD2HTR2AMAPT | |
| SCHEMBL6412800 | 0.81 | HTR1A (0.50) | SLC6A4MEN1KMT2AHTR1AHSD17B10 | |
| SCHEMBL6411215 | 0.79 | HTR1A (0.49) | SLC6A4MEN1KMT2AHTR1ATSHR | |
| SCHEMBL6411210 | 0.78 | HTR1A (0.43) | SLC6A4MEN1KMT2AHTR1AHSD17B10 | |
| SCHEMBL6411406 | 0.78 | GAA (0.55) | SLC6A4HTR1AGAA | |
| SCHEMBL6410265 | 0.78 | HTR1A (0.57) | SLC6A4MEN1KMT2AHTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050065140-A1 | Serotonine reuptake inhibitor | SUMITOMO PHARMACEUTICALS COMPANY LIMITED (JP) | 2005-03-24 | — | — | US | disclosed |
| EP-1466901-A1 | SEROTONINE REUPTAKE INHIBITOR | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2004-10-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050065140-A1 | Serotonine reuptake inhibitor | HTR1A, SLC6A4, SLC6A2 | SLC6A4 2/4885ALDH1A1 828/4885HPGD 853/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.