Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MRE11 | P49959 | 1/20 | 0.51 |
| ▸ | CLK1 | P49759 | 4/20 | 0.50 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.50 |
| ▸ | DYRK1B | Q9Y463 | 4/20 | 0.50 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.50 |
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.50 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.50 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.50 |
| ▸ | CSNK2B | P67870 | 3/20 | 0.50 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.50 |
| ▸ | DYRK2 | Q92630 | 3/20 | 0.50 |
| ▸ | CLK3 | P49761 | 2/20 | 0.50 |
| ▸ | HASPIN | Q8TF76 | 2/20 | 0.50 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.50 |
| ▸ | PIM1 | P11309 | 1/20 | 0.50 |
| ▸ | MYLK2 | Q9H1R3 | 1/20 | 0.50 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.50 |
| ▸ | PIP4K2B | P78356 | 4/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3862949 | 0.85 | PIM1 (0.69) | MEN1KMT2ACLK1DYRK1ADYRK1B | |
| SCHEMBL3862951 | 0.85 | PIM1 (0.69) | MEN1KMT2ACLK1DYRK1ADYRK1B | |
| SCHEMBL497022 | 0.81 | CLK1 (0.74) | MEN1KMT2AMRE11CLK1DYRK1A | |
| SCHEMBL497023 | 0.81 | CLK1 (0.74) | MEN1KMT2AMRE11CLK1DYRK1A | |
| SCHEMBL2883201 | 0.78 | CLK1 (0.77) | MEN1KMT2AMRE11CLK1DYRK1A | |
| SCHEMBL2883203 | 0.78 | CLK1 (0.77) | MEN1KMT2AMRE11CLK1DYRK1A | |
| SCHEMBL4441520 | 0.77 | ADAMTS5 (0.46) | CLK1DYRK1ADYRK1BPIK3CDCSNK2A2 | |
| SCHEMBL14033097 | 0.77 | DYRK3 (0.70) | MEN1KMT2ACLK1DYRK1ADYRK1B | |
| SCHEMBL27602724 | 0.76 | CLK1 (0.44) | MEN1KMT2AMRE11CLK1DYRK1A | |
| SCHEMBL2882464 | 0.74 | MEN1 (0.50) | MEN1KMT2AMRE11CLK1DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050222225-A1 | Use of compounds for increasing spermatozoa motility | APPLIED RESEARCH SYSTEMS ARS HOLDING NV (NL) | 2005-10-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050222225-A1 | Use of compounds for increasing spermatozoa motility | CATSPER1, PI4KB, MAN2B2 | MEN1 3768/4885KMT2A 2969/4885MRE11 4678/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.