Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 6/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 6/20 | 0.50 |
| ▸ | BCHE | P06276 | 5/20 | 0.47 |
| ▸ | THRA | P10827 | 3/20 | 0.45 |
| ▸ | THRB | P10828 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6415462 | 0.98 | BCHE (0.49) | IGF1RALOX15BCHETHRATHRB | |
| SCHEMBL6417134 | 0.95 | IGF1R (0.47) | IGF1RALOX15BCHETHRATHRB | |
| SCHEMBL3911899 | 0.89 | IGF1R (0.52) | IGF1RALOX15THRATHRBHSP90AA1 | |
| Cyclohexane SCHEMBL28235171 | 0.86 | IGF1R (0.50) | IGF1RALOX15BCHETHRATHRB | |
| SCHEMBL12949905 | 0.85 | THRA (0.51) | IGF1RALOX15THRATHRBKDM4E | |
| SCHEMBL7247329 | 0.85 | KAT8 (0.56) | IGF1RALOX15KDM4EALDH1A1ACHE | |
| SCHEMBL27798105 | 0.85 | KAT8 (0.56) | IGF1RALOX15KDM4EALDH1A1ACHE | |
| SCHEMBL27798114 | 0.85 | KAT8 (0.56) | IGF1RALOX15KDM4EALDH1A1ACHE | |
| SCHEMBL2672717 | 0.84 | NPC1 (0.52) | IGF1RALOX15THRATHRBKDM4E | |
| SCHEMBL9500808 | 0.83 | IGF1R (0.47) | IGF1RALOX15THRATHRBHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050277700-A1 | Non-halogenated hydroxyalkyl-substituted phenol compounds, antimicrobial compositions containing the same, and methods of using the same | MCNEIL-PPC, INC | 2005-12-15 | — | — | US | disclosed |
| US-20040199028-A1 | Non-halogenated hydroxyalkyl-substituted phenol compounds, antimicrobial compositions containing the same, and methods of using the same | MCNEIL-PPC, INC | 2004-10-07 | — | — | US | disclosed |
| US-20030139478-A1 | Non-halogenated hydroxyalkyl-substituted phenol compounds, antimicrobial compositions containing the same, and methods of using the same | HARPER D SCOTT | 2003-07-24 | — | — | US | disclosed |
| WO-2003053897-A1 | NON-HALOGENATED HYDROXYALKYL-SUBSTITUTED PHENOL COMPOUNDS, ANTIMICROBIAL COMPOSITIONS CONTAINING THE SAME, AND METHODS OF USING THE SAME | WARNER-LAMBERT COMPANY LLC (US) | 2003-07-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050277700-A1 | Non-halogenated hydroxyalkyl-substituted phenol compounds, antimicrobial compositions containing the same, and methods of using the same | HDHD5, TYR, NONO | IGF1R 4730/4885ALOX15 809/4885BCHE 3394/4885 |
| US-20030139478-A1 | Non-halogenated hydroxyalkyl-substituted phenol compounds, antimicrobial compositions containing the same, and methods of using the same | HDHD5, TYR, NONO | IGF1R 4730/4885ALOX15 809/4885BCHE 3394/4885 |
| US-20040199028-A1 | Non-halogenated hydroxyalkyl-substituted phenol compounds, antimicrobial compositions containing the same, and methods of using the same | HDHD5, TYR, NONO | IGF1R 4730/4885ALOX15 809/4885BCHE 3394/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.