Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDFT1 | P37268 | 1/20 | 0.45 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | PNMT | P11086 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 4/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6422777 | 0.84 | PTGS1 (0.50) | FDFT1KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL7090184 | 0.81 | KMT2A (0.56) | KDM4EPNMTPPARGPPARAPOLB | |
| SCHEMBL6831085 | 0.81 | KMT2A (0.56) | KDM4EPNMTPPARGPPARAPOLB | |
| SCHEMBL7090175 | 0.81 | KMT2A (0.56) | KDM4EPNMTPPARGPPARAPOLB | |
| Hydrochloric Acid SCHEMBL7090826 | 0.80 | KMT2A (0.55) | KDM4EPNMTPPARGPPARAPOLB | |
| Hydrochloric Acid SCHEMBL7090645 | 0.80 | KMT2A (0.55) | KDM4EPNMTPPARGPPARAPOLB | |
| SCHEMBL6034137 | 0.80 | FNTA (0.44) | FDFT1PGRPPARGPPARALTA4H | |
| SCHEMBL6034129 | 0.80 | HTT (0.48) | ALDH1A1MEN1HTTKMT2ASMN1; SMN2 | |
| SCHEMBL6420384 | 0.79 | FNTA (0.47) | FDFT1PGRKMT2ASMN1; SMN2LTA4H | |
| SCHEMBL9074029 | 0.75 | PNMT (0.75) | KDM4EPNMTPPARGPPARAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050038000-A1 | Methods and compositions for the treatment of amyloid-and epileptogenesis-associated diseases | BELLUS HEALTH (INTERNATIONAL) LIMITED (CH) | 2005-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050038000-A1 | Methods and compositions for the treatment of amyloid-and epileptogenesis-associated diseases | APP, PSEN1, PSEN2 | FDFT1 608/4885EPAS1 3622/4885KDM4E 3632/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.