Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23660488 | 0.80 | OPRM1 (0.32) | — | |
| SCHEMBL21846908 | 0.80 | — | — | |
| SCHEMBL10710668 | 0.76 | LMNA (0.35) | LMNA | |
| SCHEMBL4533971 | 0.75 | — | — | |
| SCHEMBL4567343 | 0.73 | ACHE (0.31) | — | |
| SCHEMBL31295849 | 0.72 | LMNA (0.33) | LMNA | |
| SCHEMBL28220323 | 0.72 | — | — | |
| SCHEMBL8960831 | 0.72 | LMNA (0.35) | LMNA | |
| SCHEMBL4595867 | 0.71 | CA1 (0.33) | LMNA | |
| SCHEMBL9547934 | 0.69 | GRIK1 (0.32) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050287594-A1 | Activity-based probes having specificity to the active form of enzymes and receptors; screening for desired biological activities or target proteins | SCRIPPS RESEARCH INSTITUTE, THE | 2005-12-29 | — | — | US | disclosed |