Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 1/20 | 0.45 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 8/20 | 0.40 |
| ▸ | PDE4A | P27815 | 6/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 6/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 6/20 | 0.40 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.37 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
| ▸ | ACSL3 | O95573 | 1/20 | 0.34 |
| ▸ | ACSL1 | P33121 | 1/20 | 0.34 |
| ▸ | ACSL6 | Q9UKU0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6414956 | 0.89 | KAT2B (0.46) | KAT2BBAZ2BPDE4DPDE4APDE4B | |
| SCHEMBL6419778 | 0.89 | KAT2B (0.46) | KAT2BBAZ2BPDE4DPDE4APDE4B | |
| SCHEMBL6414486 | 0.73 | FLT3 (0.43) | TBK1ACSL3ACSL1ACSL6 | |
| SCHEMBL1377003 | 0.67 | KAT2B (0.69) | KAT2BBAZ2BPDE4DPDE4APDE4B | |
| SCHEMBL25393148 | 0.66 | RAB9A (0.54) | — | |
| SCHEMBL8890812 | 0.65 | KAT2B (0.71) | KAT2BBAZ2BPDE4D | |
| SCHEMBL6417131 | 0.65 | RAB9A (0.58) | — | |
| SCHEMBL13692329 | 0.64 | KAT2B (0.74) | KAT2BBAZ2BPDE4DPDE4APDE4B | |
| SCHEMBL558490 | 0.64 | KAT2B (0.60) | KAT2BBAZ2BPDE4DPDE4APDE4B | |
| SCHEMBL19837798 | 0.64 | KAT2B (0.56) | KAT2BBAZ2BPDE4DPDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005118584-A2 | SAFRAMYCIN ANALOGS AS THERAPEUTIC AGENTS IN THE TREATMENT OF CANCER | AXYS PHARMACEUTICALS, INC. (US) | 2005-12-15 | — | — | WO | disclosed |