Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 1/20 | 0.46 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 9/20 | 0.43 |
| ▸ | TBK1 | Q9UHD2 | 3/20 | 0.41 |
| ▸ | IKBKE | Q14164 | 2/20 | 0.41 |
| ▸ | PDE4A | P27815 | 7/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 7/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 7/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.38 |
| ▸ | SCD | O00767 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6414956 | 0.90 | KAT2B (0.46) | KAT2BBAZ2BPDE4DPDE4APDE4B | |
| SCHEMBL6419774 | 0.89 | KAT2B (0.45) | KAT2BBAZ2BPDE4DTBK1PDE4A | |
| SCHEMBL1377003 | 0.74 | KAT2B (0.69) | KAT2BBAZ2BPDE4DPDE4APDE4B | |
| SCHEMBL6414487 | 0.73 | IKBKE (0.48) | TBK1IKBKE | |
| SCHEMBL7703671 | 0.71 | CYP2A6 (0.56) | ALDH1A1KMT2A | |
| SCHEMBL3484205 | 0.68 | KDM4E (0.45) | ALDH1A1KMT2A | |
| SCHEMBL2444039 | 0.68 | PDE4D (0.52) | KAT2BBAZ2BPDE4DTBK1IKBKE | |
| SCHEMBL25393148 | 0.67 | RAB9A (0.54) | ALDH1A1KMT2A | |
| SCHEMBL7703619 | 0.67 | ALB (0.44) | ALDH1A1KMT2A | |
| SCHEMBL8890812 | 0.66 | KAT2B (0.71) | KAT2BBAZ2BPDE4DALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005118584-A2 | SAFRAMYCIN ANALOGS AS THERAPEUTIC AGENTS IN THE TREATMENT OF CANCER | AXYS PHARMACEUTICALS, INC. (US) | 2005-12-15 | — | — | WO | disclosed |