Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPB1 | P04792 | 6/20 | 0.68 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16023861 | 0.85 | HSPB1 (0.71) | HSPB1HTTMEN1KMT2ATDP1 | |
| SCHEMBL8973950 | 0.84 | ACHE (0.53) | HSPB1HTTMEN1KMT2ATDP1 | |
| SCHEMBL13860335 | 0.84 | HSPB1 (0.77) | HSPB1HTTMEN1KMT2ATDP1 | |
| SCHEMBL13915777 | 0.84 | HSPB1 (0.71) | HSPB1HTTMEN1KMT2ATDP1 | |
| SCHEMBL13915781 | 0.84 | HSPB1 (0.71) | HSPB1HTTMEN1KMT2ATDP1 | |
| SCHEMBL1980566 | 0.83 | HSPB1 (0.51) | HSPB1HTTMEN1KMT2ATDP1 | |
| SCHEMBL10477049 | 0.83 | HSPB1 (0.70) | HSPB1HTTMEN1KMT2ATDP1 | |
| SCHEMBL2814306 | 0.82 | HSPB1 (0.68) | HSPB1HTTMEN1KMT2ATDP1 | |
| SCHEMBL9320395 | 0.82 | ALDH1A1 (0.58) | HSPB1HTTMEN1KMT2ATDP1 | |
| SCHEMBL364168 | 0.82 | HSPB1 (1.00) | HSPB1HTTMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1511718-A1 | N-ACYLAMINOBENZENE DERVATIVES AS SELECTIVE MONOAMINE OXIDASE B INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2005-03-09 | — | — | EP | disclosed |
| WO-2003099763-A1 | N-ACYLAMINOBENZENE DERVATIVES AS SELECTIVE MONOAMINE OXIDASE B INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2003-12-04 | — | — | WO | disclosed |