Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.50 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | JAK1 | P23458 | 1/20 | 0.41 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3712535 | 0.95 | RAB9A (0.48) | RAB9APRMT5WDR77MEN1HPGD | |
| SCHEMBL4595765 | 0.90 | DPP4 (0.48) | RAB9APRMT5WDR77MEN1HPGD | |
| SCHEMBL3718960 | 0.88 | RAB9A (0.52) | RAB9APRMT5WDR77MEN1HPGD | |
| SCHEMBL24131317 | 0.84 | RAB9A (0.52) | RAB9AMEN1HPGDKMT2AJAK2 | |
| SCHEMBL8489223 | 0.83 | ALDH1A1 (0.50) | PRMT5WDR77TSHRCA12CA1 | |
| SCHEMBL13864821 | 0.83 | ALDH1A1 (0.50) | PRMT5WDR77TSHRCA12CA1 | |
| SCHEMBL1692767 | 0.83 | RAB9A (0.45) | RAB9AMEN1HPGDKMT2AJAK2 | |
| SCHEMBL793727 | 0.83 | RAB9A (0.51) | RAB9APRMT5WDR77MEN1HPGD | |
| SCHEMBL21675613 | 0.82 | RAB9A (0.50) | RAB9AMEN1HPGDKMT2AJAK2 | |
| SCHEMBL14011496 | 0.82 | RAB9A (0.50) | RAB9APRMT5WDR77MEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1597264-A2 | ANTIPARASITIC TERPENE ALKALOIDS | Pfizer Limited (GB) | 2005-11-23 | — | — | EP | disclosed |
| WO-2004072086-A2 | ANTIPARASITIC TERPENE ALKALOIDS | PFIZER LIMITED (GB) | 2004-08-26 | — | — | WO | disclosed |