Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | BCHE | P06276 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
| ▸ | RARB | P10826 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28878440 | 0.92 | HTT (0.41) | NCF1TSHRALDH1A1LMNAHTT | |
| SCHEMBL29192744 | 0.91 | RARB (0.37) | TSHRALDH1A1GAALMNAHTT | |
| SCHEMBL28380046 | 0.88 | HTT (0.41) | NCF1TSHRALDH1A1GAALMNA | |
| SCHEMBL27511647 | 0.87 | HTT (0.44) | TSHRALDH1A1LMNAHTTMAPT | |
| SCHEMBL28541645 | 0.87 | S1PR3 (0.40) | NCF1TSHRGAALMNAHTT | |
| SCHEMBL28311125 | 0.85 | ALDH1A1 (0.43) | TSHRALDH1A1GAALMNAHTT | |
| Water SCHEMBL28355074 | 0.85 | HTT (0.42) | TSHRALDH1A1LMNAHTTMAPT | |
| SCHEMBL6204947 | 0.84 | LMNA (0.37) | TSHRALDH1A1GAALMNAHTT | |
| SCHEMBL28488096 | 0.84 | TSHR (0.39) | TSHRALDH1A1GAALMNAHTT | |
| SCHEMBL5310644 | 0.79 | TSHR (0.44) | TSHRALDH1A1LMNAHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1562598-A2 | DERIVATIVES OF GAMBOGIC ACID AND ANALOGS AS ACTIVATORS OF CASPASES AND INDUCERS OF APOPTOSIS | Cytovia, Inc. (US) | 2005-08-17 | — | — | EP | disclosed |
| WO-2004002428-A2 | DERIVATIVES OF GAMBOGIC ACID AND INDUCE APOPTOSIS | CYTOVIA, INC. (US) | 2004-01-08 | — | — | WO | disclosed |