Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CMA1 | P23946 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28311125 | 0.87 | ALDH1A1 (0.43) | TSHRMAPTALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL27886951 | 0.83 | MAPT (0.50) | TSHRPOLBMAPK1MAPTALDH1A1 | |
| SCHEMBL27511647 | 0.83 | HTT (0.44) | TSHRPOLBMAPTALDH1A1HTT | |
| SCHEMBL28645585 | 0.83 | PTPN1 (0.40) | TSHRPOLBMAPTALDH1A1HTT | |
| SCHEMBL28651157 | 0.81 | RXRA (0.35) | TSHRPOLBMAPTALDH1A1HTT | |
| Water SCHEMBL28355074 | 0.81 | HTT (0.42) | TSHRPOLBMAPTALDH1A1HTT | |
| SCHEMBL13432836 | 0.81 | MAPK1 (0.48) | TSHRPOLBMAPK1MAPTALDH1A1 | |
| SCHEMBL6204947 | 0.80 | LMNA (0.37) | TSHRPOLBMAPTALDH1A1HTT | |
| SCHEMBL28488096 | 0.80 | TSHR (0.39) | TSHRPOLBMAPTALDH1A1HTT | |
| SCHEMBL27886953 | 0.80 | CA1 (0.62) | TSHRPOLBMAPK1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107922407-A | Respiratory Syncytial Virus(RSV) inhibitor | 美迪维尔公司 | 2018-04-17 | — | — | CN | disclosed |
| CN-102439520-B | Photosensitive resin composition | ASAHI KASEI E MATERIALS CORP | 2014-08-27 | — | — | CN | disclosed |
| CN-103988127-A | Photosensitive resin composition, method for producing cured relief pattern, semiconductor device, and display device | ASAHI KASEI E MATERIALS CORP | 2014-08-13 | — | — | CN | disclosed |
| CN-102439520-A | Photosensitive resin composition | ASAHI KASEI E MATERIALS CORP | 2012-05-02 | — | — | CN | disclosed |
| CN-102229609-A | Quinazolinones as inhibitors of human phosphatidylinositol 3-kinase delta | ICOS CORP | 2011-11-02 | — | — | CN | disclosed |
| CN-101031569-A | Quinazolinones as human phosphatidylinositol 3-kinase delta inhibitors | ICOS CORP (US) | 2007-09-05 | — | — | CN | disclosed |
| WO-2007044796-A2 | PYRIDAZINONE COMPOUNDS AS CALCILYTICS | NPS PHARMACEUTICALS, INC. (US) | 2007-04-19 | — | — | WO | disclosed |