Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | SCD | O00767 | 5/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | HTR7 | P34969 | 2/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
| ▸ | HTR6 | P50406 | 2/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | HTR1D | P28221 | 1/20 | 0.30 |
| ▸ | HTR1B | P28222 | 1/20 | 0.30 |
| ▸ | HTR1F | P30939 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30656399 | 0.76 | OPRM1 (0.64) | OPRM1OPRD1OPRK1OPRL1DRD2 | |
| SCHEMBL3257479 | 0.76 | OPRM1 (0.64) | OPRM1OPRD1OPRK1OPRL1DRD2 | |
| SCHEMBL29423860 | 0.73 | DRD2 (0.63) | OPRM1OPRD1OPRK1OPRL1DRD2 | |
| SCHEMBL367111 | 0.73 | DRD2 (0.63) | OPRM1OPRD1OPRK1OPRL1DRD2 | |
| SCHEMBL3141317 | 0.73 | DRD2 (0.64) | OPRM1OPRD1OPRK1OPRL1DRD2 | |
| SCHEMBL30241555 | 0.72 | DRD2 (0.51) | OPRM1OPRD1OPRK1OPRL1DRD2 | |
| SCHEMBL3144674 | 0.71 | DRD2 (0.70) | OPRM1OPRD1OPRK1OPRL1DRD2 | |
| SCHEMBL30102638 | 0.71 | DRD2 (0.70) | OPRM1OPRD1OPRK1OPRL1DRD2 | |
| SCHEMBL3155300 | 0.71 | DRD2 (0.51) | OPRM1OPRD1OPRK1OPRL1DRD2 | |
| SCHEMBL12605572 | 0.70 | DRD2 (0.59) | OPRM1OPRD1OPRK1OPRL1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0817627-B1 | PROTEIN KINASE C INHIBITORS | LILLY CO ELI (US) | 2005-03-09 | — | — | EP | disclosed |