Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 12/20 | 0.44 |
| ▸ | CA2 | P00918 | 12/20 | 0.44 |
| ▸ | CA12 | O43570 | 11/20 | 0.44 |
| ▸ | CA9 | Q16790 | 10/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 8/20 | 0.44 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.44 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.44 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.44 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.44 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.44 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.44 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4425824 | 0.80 | ALDH1A1 (0.65) | LMNAALDH1A1TP53MAPTTDP1 | |
| SCHEMBL13597931 | 0.80 | ALDH1A1 (0.65) | LMNAALDH1A1TP53MAPTTDP1 | |
| SCHEMBL31685764 | 0.80 | ALDH1A1 (0.65) | LMNAALDH1A1TP53MAPTTDP1 | |
| SCHEMBL8205660 | 0.80 | ALDH1A1 (0.65) | LMNAALDH1A1TP53MAPTTDP1 | |
| SCHEMBL19889158 | 0.80 | ALDH1A1 (0.65) | LMNAALDH1A1TP53MAPTTDP1 | |
| SCHEMBL23982402 | 0.80 | ALDH1A1 (0.65) | LMNAALDH1A1TP53MAPTTDP1 | |
| SCHEMBL10033986 | 0.80 | ALDH1A1 (0.65) | LMNAALDH1A1TP53MAPTTDP1 | |
| SCHEMBL11423681 | 0.80 | ALDH1A1 (0.65) | LMNAALDH1A1TP53MAPTTDP1 | |
| SCHEMBL6419293 | 0.79 | LMNA (0.52) | HIF1ALMNAALDH1A1TP53MAPT | |
| SCHEMBL31685464 | 0.79 | ALDH1A1 (0.54) | HIF1ALMNAALDH1A1TP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1589028-A2 | Modified oligonucleotides, their preparation and their use | Aventis Pharma Deutschland GmbH (DE) | 2005-10-26 | — | — | EP | disclosed |
| EP-0680969-B1 | Modified oligonucleotides, their preparation and their use | AVENTIS PHARMA GMBH (DE) | 2005-07-27 | — | — | EP | disclosed |
| US-6066720-A | WITH AT LEAST ONE 8-AZAPURINE BASE; FORMS MORE STABLE HYBRIDIZATION COMPLEXES WITH NUCLEIC ACIDS; FOR ANTISENSE AGENTS, DIAGNOSTIC AGENTS, PROBES, PRIMERS | HOECHST AKTIENGESELLSCHAFT (DE) | 2000-05-23 | — | — | US | disclosed |
| EP-0680969-A2 | Modified oligonucleotides, their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-11-08 | — | — | EP | disclosed |