Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 3/20 | 0.48 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | BCL2 | P10415 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL229405 | 0.91 | CYP11B1 (0.48) | CYP11B1CYP11B2PTGS2CYP19A1MAPK14 | |
| SCHEMBL225762 | 0.85 | CYP11B1 (0.51) | CYP11B1CYP11B2PTGS2CYP19A1ALDH1A1 | |
| SCHEMBL226071 | 0.84 | CYP11B1 (0.53) | CYP11B1CYP11B2PTGS2CYP19A1ALDH1A1 | |
| SCHEMBL15876168 | 0.82 | PTGS2 (0.47) | CYP11B1CYP11B2PTGS2CYP19A1ALDH1A1 | |
| SCHEMBL15876230 | 0.81 | TDP1 (0.43) | CYP11B1CYP11B2PTGS2CYP19A1ALDH1A1 | |
| SCHEMBL6423017 | 0.80 | MAOB (0.43) | CYP11B1CYP11B2PTGS2CYP19A1RAB9A | |
| SCHEMBL228861 | 0.80 | CYP26A1 (0.47) | CYP11B1CYP11B2PTGS2CYP19A1MAPK14 | |
| SCHEMBL6423097 | 0.78 | PTGS2 (0.44) | CYP11B1CYP11B2PTGS2CYP19A1ALDH1A1 | |
| SCHEMBL227473 | 0.78 | PTGS2 (0.46) | CYP11B1CYP11B2PTGS2CYP19A1ALDH1A1 | |
| SCHEMBL226229 | 0.76 | CYP11B1 (0.50) | CYP11B1CYP11B2PTGS2CYP19A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1577288-A1 | SELECTIVE ESTROGEN RECEPTOR MODULATORS | Eisai Co., Ltd. (JP) | 2005-09-21 | — | — | EP | disclosed |