Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL225762 | 0.93 | CYP11B1 (0.51) | PTGS2KMT2AALDH1A1GAAMEN1 | |
| SCHEMBL227473 | 0.91 | PTGS2 (0.46) | PTGS2ALDH1A1GAACYP11B1CYP11B2 | |
| SCHEMBL6421445 | 0.84 | MAOB (0.49) | KMT2AALDH1A1MEN1MAPT | |
| SCHEMBL226071 | 0.83 | CYP11B1 (0.53) | PTGS2ALDH1A1CYP11B1CYP11B2RAB9A | |
| SCHEMBL227296 | 0.79 | PTGS2 (0.49) | PTGS2CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL15876168 | 0.79 | PTGS2 (0.47) | PTGS2KMT2AALDH1A1GAAMEN1 | |
| SCHEMBL229405 | 0.78 | CYP11B1 (0.48) | PTGS2KMT2AALDH1A1MEN1CYP11B1 | |
| SCHEMBL6422074 | 0.78 | CYP11B1 (0.48) | PTGS2KMT2AALDH1A1MEN1CYP11B1 | |
| SCHEMBL6361457 | 0.77 | ALDH1A1 (0.47) | PTGS2ALDH1A1GAARAB9ANPC1 | |
| SCHEMBL22568906 | 0.77 | PTGS2 (0.62) | PTGS2ALDH1A1CYP11B1CYP11B2CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1577288-A1 | SELECTIVE ESTROGEN RECEPTOR MODULATORS | Eisai Co., Ltd. (JP) | 2005-09-21 | — | — | EP | disclosed |