Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 8/20 | 0.57 |
| ▸ | FNTB | P49356 | 8/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.49 |
| ▸ | DTYMK | P23919 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16175115 | 1.00 | FNTA (0.57) | FNTAFNTBPOLBGPR119DTYMK | |
| SCHEMBL9932845 | 1.00 | FNTA (0.57) | FNTAFNTBPOLBGPR119DTYMK | |
| SCHEMBL9934271 | 0.94 | FNTA (0.58) | FNTAFNTBPOLBGPR119DTYMK | |
| SCHEMBL9963094 | 0.94 | FNTA (0.58) | FNTAFNTBPOLBGPR119DTYMK | |
| SCHEMBL9934506 | 0.83 | FNTA (0.44) | FNTAFNTBCXCR4 | |
| SCHEMBL6423382 | 0.81 | CHRNA7 (0.51) | GPR119NPC1RAB9A | |
| SCHEMBL2084608 | 0.81 | FNTA (0.51) | FNTAFNTBPOLBGPR119NPC1 | |
| SCHEMBL6421368 | 0.78 | CHRNA7 (0.50) | FNTAFNTBGPR119NPC1RAB9A | |
| SCHEMBL6421652 | 0.78 | GPR119 (0.47) | FNTAFNTBGPR119NPC1RAB9A | |
| SCHEMBL21744569 | 0.78 | CXCR4 (0.48) | FNTAFNTBPOLBCXCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1057814-B1 | TETRAHYDROBENZINDOLE DERIVATIVES | MEIJI SEIKA KAISHA (JP) | 2005-03-09 | — | — | EP | disclosed |
| CN-1129578-C | Tetrahydrobenzindole derivatives | MEIJI SEIKA KAISHA (JP) | 2003-12-03 | — | — | CN | disclosed |
| US-6498251-B1 | Tetrahydrobenzindole derivatives | MEIJI SEIKA KAISHA, LTD. (JP) | 2002-12-24 | — | — | US | disclosed |
| CN-1286683-A | Tetrahydrobenzindole derivatives | MEIJI SEIKA KAISHA (JP) | 2001-03-07 | — | — | CN | disclosed |
| EP-1057814-A1 | TETRAHYDROBENZINDOLE DERIVATIVES | Meiji Seika Kaisha, Ltd. (JP) | 2000-12-06 | — | — | EP | disclosed |