Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CFTR | P13569 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2225346 | 0.78 | CHRM3 (0.32) | MAPTTSHRLMNASMN1; SMN2NPSR1 | |
| Hydrochloric Acid SCHEMBL10854710 | 0.72 | — | — | |
| SCHEMBL48012 | 0.69 | LMNA (0.37) | L3MBTL1TSHRALDH1A1LMNACA1 | |
| SCHEMBL7035636 | 0.67 | LMNA (0.36) | L3MBTL1TSHRALDH1A1LMNACA1 | |
| SCHEMBL8417905 | 0.67 | TSHR (0.35) | MAPTL3MBTL1TSHRLMNACA1 | |
| SCHEMBL28926409 | 0.67 | CHRM3 (0.33) | L3MBTL1TSHRLMNACA1CA2 | |
| SCHEMBL6813512 | 0.64 | CHRM3 (0.31) | MAPTALDH1A1LMNACFTRHSD17B10 | |
| SCHEMBL23050146 | 0.63 | TSHR (0.41) | TSHRALDH1A1LMNASMN1; SMN2HSD17B10 | |
| Dimethyl Phthalate SCHEMBL28528385 | 0.62 | MAPT (0.70) | HPGDMAPTRAB9AL3MBTL1CASP3 | |
| Azobenzene SCHEMBL28437893 | 0.62 | RAB9A (0.89) | HPGDMAPTRAB9AL3MBTL1CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005016255-A2 | SUBSTITUTED TETRAHYDROQUINOLINES, PHENYLACETIC ACIDS AND BENZOIC ACIDS AS HEPATOCYTE NUCLEAR FACTOR 4 (HNF-4 ) MODULATOR COMPOUNDS | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2005-02-24 | — | — | WO | disclosed |