Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 7/20 | 0.35 |
| ▸ | CA1 | P00915 | 7/20 | 0.35 |
| ▸ | CA2 | P00918 | 7/20 | 0.35 |
| ▸ | CA9 | Q16790 | 7/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 7/20 | 0.35 |
| ▸ | CA7 | P43166 | 6/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.35 |
| ▸ | XDH | P47989 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL48012 | 0.98 | LMNA (0.37) | LMNACHRM3CHRM2CHRM4CHRM5 | |
| SCHEMBL11229915 | 0.79 | NFKB1 (0.39) | CA12CA1CA2CA9CA14 | |
| SCHEMBL1682242 | 0.79 | CA12 (0.43) | LMNACA12CA1CA2CA9 | |
| SCHEMBL3205528 | 0.79 | ALDH1A1 (0.32) | TSHRALDH1A1 | |
| SCHEMBL47924 | 0.78 | CA12 (0.42) | LMNACA12CA1CA2CA9 | |
| SCHEMBL3110549 | 0.77 | SERPINE1 (0.37) | TDP1TSHR | |
| SCHEMBL28926409 | 0.77 | CHRM3 (0.33) | LMNACHRM3CHRM2CHRM4CHRM5 | |
| SCHEMBL8417905 | 0.77 | TSHR (0.35) | LMNACHRM3CHRM2CHRM4CHRM5 | |
| SCHEMBL8187265 | 0.76 | LMNA (0.44) | LMNACA1CA2KDM4ETDP1 | |
| SCHEMBL47935 | 0.75 | ALDH1A1 (0.43) | LMNACHRM1KDM4ETDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1468677-B1 | An antireflux syrup | DMG ITALIA SRL (IT) | 2012-08-08 | — | — | EP | disclosed |
| EP-1468677-A2 | An antireflux syrup | D.M.G. Italia Srl (IT) | 2004-10-20 | — | — | EP | disclosed |