Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5137200 | 0.81 | KDM4E (0.31) | RAB9A | |
| SCHEMBL1835615 | 0.81 | NPSR1 (0.31) | RAB9A | |
| SCHEMBL25181136 | 0.72 | GNAI3 (0.33) | — | |
| SCHEMBL642662 | 0.72 | — | — | |
| SCHEMBL643401 | 0.69 | — | — | |
| SCHEMBL21752643 | 0.68 | — | — | |
| SCHEMBL1857923 | 0.68 | GAA (0.32) | — | |
| SCHEMBL642699 | 0.66 | ALDH1A1 (0.35) | — | |
| SCHEMBL16538836 | 0.64 | CYP4F2 (0.32) | — | |
| SCHEMBL146254 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1960347-B1 | 17-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 3 (17BETA-HSD3) INHIBITORS | STERIX LTD (GB) | 2012-06-20 | — | — | EP | disclosed |
| US-8119627-B2 | Heterocyclic compounds as inhibitors of 17beta-HSD3 | STERIX LIMITED (GB) | 2012-02-21 | — | — | US | disclosed |