Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1835615 | 0.84 | NPSR1 (0.31) | KDM4EPKMRAB9A | |
| SCHEMBL642246 | 0.81 | RAB9A (0.31) | RAB9A | |
| SCHEMBL29156294 | 0.65 | — | — | |
| SCHEMBL21752643 | 0.65 | — | — | |
| SCHEMBL10500455 | 0.62 | TSHR (0.36) | RAB9A | |
| SCHEMBL25253310 | 0.61 | KDM4E (0.30) | KDM4EPKM | |
| SCHEMBL17049040 | 0.61 | CPB2 (0.39) | KDM4EPKM | |
| SCHEMBL20504486 | 0.60 | HSD17B10 (0.35) | — | |
| SCHEMBL20456819 | 0.60 | GNAI3 (0.37) | — | |
| SCHEMBL8550083 | 0.60 | KDM4E (0.36) | KDM4EPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1960347-A2 | 17-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 3 (17BETA-HSD3) INHIBITORS | Sterix Limited (GB) | 2008-08-27 | — | — | EP | disclosed |
| WO-2007003934-A2 | 17BETA-HYDR0XYSTER0ID DEHYDROGENASE TYPE 3 (17BETA-HSD3 ) INHIBITORS | STERIX LIMITED (GB) | 2007-01-11 | — | — | WO | disclosed |