Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.42 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | AXL | P30530 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | NAT1 | P18440 | 3/20 | 0.41 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.41 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.41 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.41 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5981739 | 0.86 | PTGER1 (0.42) | TRIM24TRIM33BRD4AXLCA12 | |
| SCHEMBL29434205 | 0.85 | TP53 (0.43) | TRPA1PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL4520753 | 0.85 | TP53 (0.43) | TRPA1PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL6048487 | 0.84 | BACE1 (0.45) | TRIM24TRIM33BRD4AXLCA12 | |
| SCHEMBL11647426 | 0.83 | PTGER1 (0.53) | TRPA1PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL5490744 | 0.83 | TRIM24 (0.52) | TRIM24TRIM33BRD4AXLCA12 | |
| Hydrochloric Acid SCHEMBL6048532 | 0.83 | BACE1 (0.44) | TRIM24TRIM33BRD4AXLCA12 | |
| SCHEMBL1746687 | 0.82 | BRD4 (0.51) | TRIM24TRIM33BRD4CA12CA1 | |
| SCHEMBL13250832 | 0.80 | TRIM24 (0.53) | TRIM24TRIM33BRD4AXLCA12 | |
| SCHEMBL3479559 | 0.79 | BRD4 (0.47) | TRIM24TRIM33BRD4AXLCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1513793-A1 | NOVEL LIGANDS THAT ARE INHIBITORS OF THE RAR RECEPTORS, PROCESS FOR PREPARING THEM AND USE THEREOF IN HUMAN MEDICINE AND IN COSMETICS | Galderma Research & Development, S.N.C. (FR) | 2005-03-16 | — | — | EP | disclosed |
| WO-2003101928-A1 | NOVEL LIGANDS THAT ARE INHIBITORS OF THE RAR RECEPTORS, PROCESS FOR PREPARING THEM AND USE THEREOF IN HUMAN MEDICINE AND IN COSMETICS | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2003-12-11 | — | — | WO | disclosed |