Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.54 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 9/20 | 0.48 |
| ▸ | MAOA | P21397 | 4/20 | 0.48 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.47 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16379078 | 1.00 | CYP1A2 (0.56) | CYP1A2LMNAPTGS1SLC6A2CYP2C19 | |
| SCHEMBL16379079 | 1.00 | CYP1A2 (0.56) | CYP1A2LMNAPTGS1SLC6A2CYP2C19 | |
| SCHEMBL2007390 | 0.79 | CYP1A2 (0.67) | CYP1A2LMNAPTGS1SLC6A2CYP2C19 | |
| SCHEMBL1834526 | 0.79 | CYP1A2 (0.67) | CYP1A2LMNAPTGS1SLC6A2CYP2C19 | |
| SCHEMBL4674930 | 0.78 | MEN1 (0.70) | CYP1A2LMNAPTGS1SLC6A2CYP2C19 | |
| SCHEMBL1186369 | 0.78 | CYP1A2 (0.60) | CYP1A2LMNAPTGS1SLC6A2CYP2C19 | |
| SCHEMBL2446166 | 0.76 | CYP1A2 (0.58) | CYP1A2LMNAPTGS1SLC6A2CYP2C19 | |
| SCHEMBL10030221 | 0.76 | CYP1A2 (0.58) | CYP1A2LMNAPTGS1SLC6A2CYP2C19 | |
| Monobenzone SCHEMBL8450838 | 0.72 | LMNA (1.00) | CYP1A2LMNAPTGS1SLC6A2CYP2C19 | |
| Monobenzone SCHEMBL11272996 | 0.72 | LMNA (1.00) | CYP1A2LMNAPTGS1SLC6A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9255054-B2 | High-yield synthesis of p-(benzyloxy)calix[6, 7,8]arenes | UNIVERSITE PARIS-SUD XI (FR) | 2016-02-09 | — | — | US | disclosed |
| US-20150011798-A1 | HIGH-YIELD SYNTHESIS OF P-(BENZYLOXY)CALIX[6, 7,8]ARENES | UNIVERSITE PARIS-SUD XI (FR) | 2015-01-08 | — | — | US | disclosed |
| EP-1200391-B1 | CALIXARENE ACETAMIDO DERIVATIVES, PREPARATION AND USE THEREOF FOR EXTRACTING STRONTIUM | COMMISSARIAT ENERGIE ATOMIQUE (FR) | 2005-10-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150011798-A1 | HIGH-YIELD SYNTHESIS OF P-(BENZYLOXY)CALIX[6, 7,8]ARENES | BRIX1, CBX2, CANX | CYP1A2 1532/4885LMNA 1625/4885PTGS1 912/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.