Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRDMT1 | O14717 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.43 |
| ▸ | SLC29A1 | Q99808 | 6/20 | 0.43 |
| ▸ | PI4KA | P42356 | 2/20 | 0.42 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.42 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.42 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.42 |
| ▸ | NNMT | P40261 | 1/20 | 0.41 |
| ▸ | SLC28A3 | Q9HAS3 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.41 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.41 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL441536 | 0.87 | EGFR (0.47) | ADORA2AADORA3SLC29A1PI4KAPI4K2B | |
| SCHEMBL31644935 | 0.87 | EGFR (0.47) | ADORA2AADORA3SLC29A1PI4KAPI4K2B | |
| SCHEMBL1271977 | 0.87 | CA1 (0.44) | ADORA2AADORA3SLC29A1PI4KAPI4K2B | |
| SCHEMBL4916912 | 0.86 | ADORA3 (0.48) | ADORA2AADORA3SLC29A1PI4KAPI4K2B | |
| SCHEMBL5179761 | 0.86 | ABCB1 (0.51) | ADORA2AADORA3SLC29A1PI4KAPI4K2B | |
| SCHEMBL337874 | 0.86 | ADORA3 (0.45) | TRDMT1ADORA2AADORA3SLC29A1PI4KA | |
| SCHEMBL30041710 | 0.86 | DOT1L (0.45) | ADORA2AADORA3SLC29A1PI4KAPI4K2B | |
| SCHEMBL6425800 | 0.85 | ADORA3 (0.44) | ADORA2AADORA3SLC29A1PI4KAPI4K2B | |
| SCHEMBL9501856 | 0.83 | EGFR (0.43) | ADORA2AADORA3SLC29A1PI4KAPI4K2B | |
| SCHEMBL8714851 | 0.83 | ADORA2A (0.44) | TRDMT1ADORA2AADORA3SLC29A1PI4KA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0506830-B1 | UNCHARGED MORPHOLINO-BASED POLYMERS HAVING PHOSPHOROUS-CONTAINING CHIRAL INTERSUBUNIT LINKAGES | AVI BIOPHARMA INC (US) | 2005-12-14 | — | — | EP | disclosed |
| EP-0962463-B1 | Uncharged morpholino-based polymers having phosphorus-containing chiral intersubunit linkages | ANTIVIRALS INC (US) | 2002-07-10 | — | — | EP | disclosed |
| EP-0962463-A1 | Uncharged morpholino-based polymers having phosphorus-containing chiral intersubunit linkages | ANTIVIRALS INC. (US) | 1999-12-08 | — | — | EP | disclosed |
| EP-0639582-B1 | Polynucleotide assay reagent and method | ANTIVIRALS INC (US) | 1998-09-16 | — | — | EP | disclosed |
| EP-0506845-B1 | UNCHARGED MORPHOLINO-BASED POLYMERS HAVING ACHIRAL INTERSUBUNIT LINKAGES | ANTIVIRALS INC (US) | 1998-03-18 | — | — | EP | disclosed |
| US-5521063-A | Polynucleotide reagent containing chiral subunits and methods of use | ANTIVIRALS INC. (US) | 1996-05-28 | — | — | US | disclosed |
| US-5470974-A | Uncharged polynucleotide-binding polymers | NEU-GENE DEVELOPMENT GROUP (US) | 1995-11-28 | — | — | US | disclosed |
| EP-0215942-B1 | POLYNUCLEOTIDE ASSAY REAGENT AND METHOD | ANTIVIRALS INC (US) | 1995-07-12 | — | — | EP | disclosed |
| EP-0639582-A2 | Polynucleotide assay reagent and method | ANTIVIRALS INC. (US) | 1995-02-22 | — | — | EP | disclosed |
| US-5378841-A | Alpha-morpholino ribonucleoside derivatives and polymers thereof | ANTIVIRALS INC. (US) | 1995-01-03 | — | — | US | disclosed |
| US-5142047-A | Morpholino nucleosides for blocking targeted genetic sequence | ANTI-GENE DEVELOPMENT GROUP (US) | 1992-08-25 | — | — | US | disclosed |
| US-5034506-A | Polymers for the determination of genetic sequences and viral diseases | ANTI-GENE DEVELOPMENT GROUP (US) | 1991-07-23 | — | — | US | disclosed |
| WO-1991009073-A1 | UNCHARGED MORPHOLINO-BASED POLYMERS HAVING ACHIRAL INTERSUBUNIT LINKAGES | ANTI-GENE DEVELOPMENT GROUP (US) | 1991-06-27 | — | — | WO | disclosed |
| WO-1991009033-A1 | UNCHARGED MORPHOLINO-BASED POLYMERS HAVING PHOSPHOROUS-CONTAINING CHIRAL INTERSUBUNIT LINKAGES | ANTI-GENE DEVELOPMENT GROUP (US) | 1991-06-27 | — | — | WO | disclosed |
| EP-0216860-A4 | STEREOREGULAR POLYNUCLEOTIDE-BINDING POLYMERS. | SUMMERTON JAMES (US) | 1989-02-22 | — | — | EP | disclosed |
| EP-0215942-A4 | POLYNUCLEOTIDE ASSAY REAGENT AND METHOD. | SUMMERTON JAMES | 1988-08-23 | — | — | EP | disclosed |
| EP-0216860-A1 | STEREOREGULAR POLYNUCLEOTIDE-BINDING POLYMERS. | SUMMERTON JAMES (US) | 1987-04-08 | — | — | EP | disclosed |
| EP-0215942-A1 | POLYNUCLEOTIDE ASSAY REAGENT AND METHOD. | SUMMERTON JAMES | 1987-04-01 | — | — | EP | disclosed |
| WO-1986005518-A1 | STEREOREGULAR POLYNUCLEOTIDE-BINDING POLYMERS | SUMMERTON JAMES | 1986-09-25 | — | — | WO | disclosed |
| WO-1986005519-A1 | POLYNUCLEOTIDE ASSAY REAGENT AND METHOD | SUMMERTON JAMES | 1986-09-25 | — | — | WO | disclosed |