Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.45 |
| ▸ | SLC28A2 | O43868 | 2/20 | 0.44 |
| ▸ | PI4KA | P42356 | 3/20 | 0.43 |
| ▸ | PI4K2B | Q8TCG2 | 3/20 | 0.43 |
| ▸ | PI4K2A | Q9BTU6 | 3/20 | 0.43 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.43 |
| ▸ | TRDMT1 | O14717 | 1/20 | 0.43 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.42 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.42 |
| ▸ | GAPDH | P04406 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.42 |
| ▸ | STAT6 | P42226 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL441536 | 0.89 | EGFR (0.47) | ADORA3ADORA2ASLC28A2PI4KAPI4K2B | |
| SCHEMBL31644935 | 0.89 | EGFR (0.47) | ADORA3ADORA2ASLC28A2PI4KAPI4K2B | |
| SCHEMBL6425800 | 0.88 | ADORA3 (0.44) | ADORA3ADORA2ASLC28A2PI4KAPI4K2B | |
| SCHEMBL4916912 | 0.88 | ADORA3 (0.48) | ADORA3ADORA2ASLC28A2PI4KAPI4K2B | |
| SCHEMBL30041710 | 0.87 | DOT1L (0.45) | ADORA3ADORA2ASLC28A2PI4KAPI4K2B | |
| SCHEMBL1271977 | 0.86 | CA1 (0.44) | ADORA3ADORA2ASLC28A2PI4KAPI4K2B | |
| SCHEMBL9501856 | 0.86 | EGFR (0.43) | ADORA3ADORA2ASLC28A2PI4KAPI4K2B | |
| SCHEMBL6423121 | 0.86 | TRDMT1 (0.44) | ADORA3ADORA2ASLC28A2PI4KAPI4K2B | |
| SCHEMBL5179761 | 0.86 | ABCB1 (0.51) | ADORA3ADORA2ASLC28A2PI4KAPI4K2B | |
| SCHEMBL30406718 | 0.84 | EGFR (0.42) | ADORA3ADORA2ASLC28A2PI4KAPI4K2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8097711-B2 | nucleoside monomers protected with thioether substituted aryl carbonate protecting groups; oligonucleotides, using such protected nucleoside monomer monomers, as well as nucleic acids | AGILENT TECHNOLOGIES, INC. (US) | 2012-01-17 | — | — | US | disclosed |
| US-20080146787-A1 | Thioether substituted aryl carbonate protecting groups | AGILENT TECHNOLOGIES, INC. | 2008-06-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080146787-A1 | Thioether substituted aryl carbonate protecting groups | NSUN2, NSUN3, TRDMT1 | ADORA3 166/4885ADORA2A 612/4885SLC28A2 40/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.