SCHEMBL6423951

SCHEMBL6423951

c1coc(N2CCCN2)n1

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HTR2C P28335 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6031390 0.76 ROCK2 (0.30)
SCHEMBL914723 0.74
SCHEMBL3365138 0.73 HTR2C (0.47) HTR2C
SCHEMBL27490517 0.70 HTR2C (0.41) HTR2C
SCHEMBL5313919 0.70 CHKA (0.37)
SCHEMBL28486034 0.68 ALDH1A1 (0.50)
SCHEMBL28179378 0.67 HSD11B1 (0.39)
SCHEMBL4706765 0.67
SCHEMBL4062564 0.65
SCHEMBL8068542 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102675258-A Novel taxane compound and preparation method thereof JIANGSU HONGDOUSHAN BIOLOG TECHNOLOGY CO LTD 2012-09-19 CN claimed
CN-102675258-A Novel taxane compound and preparation method thereof JIANGSU HONGDOUSHAN BIOLOG TECHNOLOGY CO LTD 2012-09-19 CN disclosed
CN-102516127-A One-pot synthesis method of N-substituted glycine JIANGSU YEW PHARMACEUTICAL CO LTD 2012-06-27 CN disclosed
CN-102443048-A Synthetic method of 5-membered cyclopeptide JIANGSU YEW PHARMACEUTICAL CO LTD 2012-05-09 CN disclosed
CN-100393299-C Use of an inhibitor of 15-hydroxyprostaglandin dehydrogenasein order to stimulate pigmentation of the skin or skin appendages OREAL (FR) 2008-06-11 CN disclosed
CN-1774229-A Use of an inhibitor of 15-hydroxyprostaglandin dehydrogenasein order to stimulate pigmentation of the skin or skin appendages OREAL (FR) 2006-05-17 CN disclosed
EP-1594438-A2 USE OF AN INHIBITOR OF 15-HYDROXYPROSTAGLANDIN DEHYDROGENASE IN ORDER TO STIMULATE PIGMENTATION OF THE SKIN OR SKIN APPENDAGES L'OREAL (FR) 2005-11-16 EP disclosed
WO-2004073594-A2 USE OF AN INHIBITOR OF 15-HYDROXYPROSTAGLANDIN DEHYDROGENASE IN ORDER TO STIMULATE PIGMENTATION OF THE SKIN OR SKIN APPENDAGES L'OREAL (FR) 2004-09-02 WO disclosed
CN-1154696-A Deacetoxytaxol derivative DAIICHI SEIYAKU CO (JP) 1997-07-16 CN disclosed