SCHEMBL6423974

SCHEMBL6423974

COc1c(Br)ccc(Br)c1Br

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 7/20 0.54
CA4 P22748 7/20 0.54
NQO2 P16083 2/20 0.44
TUBB1 Q9H4B7 4/20 0.38
KDM4E B2RXH2 1/20 0.38
ALDH1A1 P00352 1/20 0.38
MAPK1 P28482 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
CA1 P00915 5/20 0.37
CA6 P23280 5/20 0.37
ALOX5AP P20292 1/20 0.37
FEN1 P39748 1/20 0.37
TUBB4A P04350 2/20 0.36
TUBB P07437 2/20 0.36
TUBA3C P0DPH7 2/20 0.36
TUBA1B P68363 2/20 0.36
TUBA4A P68366 2/20 0.36
TUBB4B P68371 2/20 0.36
TUBB3 Q13509 2/20 0.36
TUBB2A Q13885 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL127769 0.85 CA2 (0.55) CA2CA4NQO2TUBB1KDM4E
SCHEMBL9213947 0.82 CA2 (0.43) CA2CA4NQO2TUBB1KDM4E
SCHEMBL9109330 0.82 TUBB1 (0.47) CA2CA4NQO2TUBB1KDM4E
SCHEMBL1628136 0.82 CA2 (0.54) CA2CA4NQO2TUBB1KDM4E
SCHEMBL7484583 0.82 CA2 (0.48) CA2CA4NQO2TUBB1KDM4E
SCHEMBL2171111 0.80 ALOX15 (0.52) CA2CA4NQO2KDM4EALDH1A1
SCHEMBL10740406 0.80 CA2 (0.46) CA2CA4NQO2TUBB1KDM4E
SCHEMBL7219358 0.78 KDM4E (0.50) CA2CA4NQO2TUBB1KDM4E
SCHEMBL9292546 0.76 NQO2 (0.42) CA2CA4NQO2TUBB1KDM4E
SCHEMBL23706024 0.75 PRKDC (0.46) CA2CA4NQO2TUBB1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1575790-A Use of 1-nonen-3-one as a flavouring agent NESTLE SA (CH) 2005-02-09 CN disclosed
EP-1006813-B1 USE OF 1-NONEN-3-ONE AS A FLAVOURING AGENT NESTLE SA (CH) 2005-02-02 EP disclosed
US-6296889-B1 Use of 1-nonen-3-one for aroma/flavor enhancement NESTEC S.A. (CH) 2001-10-02 US disclosed