SCHEMBL7219358

SCHEMBL7219358

COc1c(Br)ccc2c(OC)c(Br)ccc12

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.50
ALDH1A1 P00352 1/20 0.50
MAPK1 P28482 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
NQO2 P16083 2/20 0.44
CA2 P00918 3/20 0.42
CA4 P22748 2/20 0.42
ALOX5AP P20292 1/20 0.41
FEN1 P39748 1/20 0.41
MAPT P10636 2/20 0.39
MEN1 O00255 1/20 0.39
USP2 O75604 1/20 0.39
ALOX15 P16050 1/20 0.39
KMT2A Q03164 1/20 0.39
TUBB1 Q9H4B7 4/20 0.38
TUBB4A P04350 2/20 0.36
TUBB P07437 2/20 0.36
TUBA3C P0DPH7 2/20 0.36
TUBA1B P68363 2/20 0.36
TUBA4A P68366 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19465429 0.87 KDM4E (0.39) KDM4EALDH1A1MAPK1SMN1; SMN2NQO2
SCHEMBL127769 0.85 CA2 (0.55) KDM4EALDH1A1MAPK1SMN1; SMN2NQO2
SCHEMBL19462419 0.79 THRA (0.44) MAPTMEN1USP2ALOX15KMT2A
SCHEMBL6423974 0.78 CA2 (0.54) KDM4EALDH1A1MAPK1SMN1; SMN2NQO2
SCHEMBL23060935 0.77 CYP1A2 (0.43) KDM4EALDH1A1MAPK1NQO2CA2
SCHEMBL15266968 0.77 CYP1A2 (0.48) KDM4EMAPTMEN1KMT2ATUBB1
SCHEMBL8200761 0.77 ALDH1A1 (0.50) KDM4EALDH1A1MAPK1SMN1; SMN2NQO2
SCHEMBL9292546 0.76 NQO2 (0.42) KDM4EALDH1A1MAPK1SMN1; SMN2NQO2
SCHEMBL24608163 0.74 ALOX5AP (0.37) NQO2ALOX5APFEN1MAPTMEN1
SCHEMBL25249996 0.74 PDE3B (0.45) KDM4EALDH1A1SMN1; SMN2NQO2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11839141-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-12-05 US disclosed
US-11839141-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-12-05 US disclosed
US-11839141-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-12-05 US disclosed
US-20230043458-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-02-09 US disclosed
US-20230043458-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-02-09 US disclosed
US-11469384-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2022-10-11 US disclosed
US-11053267-B2 Electrochromic compound, electrochromic composition, and display element RICOH COMPANY, LTD. (JP) 2021-07-06 US disclosed
US-20200216478-A1 ELECTROCHROMIC COMPOUND, ELECTROCHROMIC COMPOSITION, AND DISPLAY ELEMENT SAGISAKA TOSHIYA (JP) 2020-07-09 US disclosed
CN-111138495-A Organic electroluminescent material and device 环球展览公司 2020-05-12 CN disclosed
US-20200144519-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2020-05-07 US disclosed
US-8754188-B2 Semiconducting compounds and devices incorporating same NORTHWESTERN UNIVERSITY (US) 2014-06-17 US disclosed
WO-2014069675-A1 ELECTROCHROMIC COMPOUND, ELECTROCHROMIC COMPOSITION, AND DISPLAY ELEMENT RICOH COMPANY, LTD. (JP) 2014-05-08 WO disclosed
US-20120264906-A1 SEMICONDUCTING COMPOUNDS AND DEVICES INCORPORATING SAME UNITED STATES DEPARTMENT OF ENERGY 2012-10-18 US disclosed
US-20120264906-A1 SEMICONDUCTING COMPOUNDS AND DEVICES INCORPORATING SAME UNITED STATES DEPARTMENT OF ENERGY 2012-10-18 US disclosed
US-20120264906-A1 SEMICONDUCTING COMPOUNDS AND DEVICES INCORPORATING SAME UNITED STATES DEPARTMENT OF ENERGY 2012-10-18 US disclosed
WO-2012129511-A2 SEMICONDUCTING COMPOUNDS AND DEVICES INCORPORATING SAME NORTHWESTERN UNIVERSITY (US) 2012-09-27 WO disclosed
US-20070287821-A1 Synthesis of Polynaphthalenes and Their Use BASF AKTIENGESELLSCHAFT (DE) 2007-12-13 US disclosed
US-6617462-B1 Di- and tetra-methoxy-bis(2-thienyl)naphthalene monomers that can be electropolymerized to form conductive polymers THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE 2003-09-09 US disclosed
US-6359149-B1 Bithienylnaphthalene- and bis(3,4-ethylenedioxythienyl)naphthalene-based monomers and polymers THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE 2002-03-19 US disclosed
US-6291621-B1 FOR PRODUCING THIN FILMS AND COATINGS USEFUL IN ELECTROCHROMIC APPLICATIONS; ELECTROCONDUCTIVITY, ELECTRODES THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE 2001-09-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120264906-A1 SEMICONDUCTING COMPOUNDS AND DEVICES INCORPORATING SAME TST, NECTIN4, ICMT KDM4E 1249/4885ALDH1A1 916/4885MAPK1 2972/4885
US-20230043458-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OSBP, OCIAD1, OCIAD2 KDM4E 4190/4885ALDH1A1 345/4885MAPK1 3350/4885
US-20200144519-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OSBP, OCIAD1, OCIAD2 KDM4E 4190/4885ALDH1A1 345/4885MAPK1 3350/4885
US-11839141-B2 Organic electroluminescent materials and devices OSBP, OCIAD1, OCIAD2 KDM4E 4190/4885ALDH1A1 345/4885MAPK1 3350/4885
US-20200216478-A1 ELECTROCHROMIC COMPOUND, ELECTROCHROMIC COMPOSITION, AND DISPLAY ELEMENT SCN11A, H1-10, H1-2 KDM4E 1639/4885ALDH1A1 4158/4885MAPK1 2894/4885
US-11469384-B2 Organic electroluminescent materials and devices OSBP, OCIAD1, OCIAD2 KDM4E 4190/4885ALDH1A1 345/4885MAPK1 3350/4885
US-11053267-B2 Electrochromic compound, electrochromic composition, and display element SCN11A, H1-10, H1-2 KDM4E 1639/4885ALDH1A1 4158/4885MAPK1 2894/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.