Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | GHSR | Q92847 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6422682 | 0.86 | MAOA (0.52) | SMN1; SMN2KMT2ANR1H2MEN1ESR2 | |
| SCHEMBL7619697 | 0.84 | SMN1; SMN2 (0.70) | SMN1; SMN2KMT2AMEN1NPC1POLB | |
| SCHEMBL18617672 | 0.84 | LMNA (0.45) | SMN1; SMN2KMT2ANR1H2MEN1ESR2 | |
| SCHEMBL31505338 | 0.82 | ESR2 (0.56) | SMN1; SMN2NR1H2ESR2GHSR | |
| SCHEMBL21470623 | 0.82 | ESR2 (0.56) | SMN1; SMN2KMT2ANR1H2ESR2NPC1 | |
| SCHEMBL24528817 | 0.82 | ESR2 (0.56) | SMN1; SMN2NR1H2ESR2GHSR | |
| SCHEMBL30645355 | 0.82 | ESR2 (0.56) | SMN1; SMN2NR1H2ESR2GHSR | |
| SCHEMBL21470624 | 0.82 | ESR2 (0.56) | SMN1; SMN2KMT2ANR1H2ESR2NPC1 | |
| SCHEMBL31505332 | 0.82 | ESR2 (0.56) | SMN1; SMN2NR1H2ESR2GHSR | |
| SCHEMBL31505408 | 0.82 | ESR2 (0.56) | SMN1; SMN2NR1H2ESR2GHSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1057814-B1 | TETRAHYDROBENZINDOLE DERIVATIVES | MEIJI SEIKA KAISHA (JP) | 2005-03-09 | — | — | EP | disclosed |