SCHEMBL6424581

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL8349103	1.00	TAAR1 (0.42)	TAAR1NR3C1PGRNR3C2PPARG
	SCHEMBL14402393	0.84	TAAR1 (0.39)	TAAR1NR3C1PGRNR3C2PPARG
	SCHEMBL6047669	0.84	TAAR1 (0.39)	TAAR1NR3C1PGRNR3C2PPARG
	SCHEMBL13849916	0.84	TAAR1 (0.39)	TAAR1NR3C1PGRNR3C2PPARG
	SCHEMBL27531705	0.83	CYP1A2 (0.50)	TAAR1PPARGPPARALMNADNM1
	SCHEMBL8418317	0.83	CYP1A2 (0.50)	TAAR1PPARGPPARALMNADNM1
	SCHEMBL15319160	0.82	TAAR1 (0.38)	TAAR1PPARGPPARADNM1SLC6A2
	SCHEMBL15319376	0.82	TAAR1 (0.42)	TAAR1PPARGPPARAKMT2ALMNA
	SCHEMBL11538150	0.82	TAAR1 (0.50)	TAAR1PPARGPPARAKMT2ADNM1
	SCHEMBL15319281	0.81	TAAR1 (0.37)	TAAR1PPARGPPARADNM1SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.