Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 2/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6424040 | 0.87 | ESR1 (0.55) | — | |
| SCHEMBL229420 | 0.83 | BACE1 (0.58) | FLT3LTA4HHRH3KDM4EALDH1A1 | |
| SCHEMBL229153 | 0.78 | LTA4H (0.61) | LTA4HHRH3 | |
| SCHEMBL227235 | 0.78 | LTA4H (0.61) | LTA4HHRH3 | |
| SCHEMBL15474972 | 0.77 | LTA4H (0.54) | MAOBACHELTA4HHRH3ALDH1A1 | |
| SCHEMBL7092816 | 0.77 | ESR1 (0.63) | ACHEALDH1A1KMT2A | |
| SCHEMBL6749914 | 0.77 | BCHE (0.58) | MAOBACHEHRH3KDM4EALDH1A1 | |
| SCHEMBL226318 | 0.77 | ESR1 (0.60) | FLT3LTA4HKDM4E | |
| SCHEMBL227226 | 0.77 | ESR1 (0.60) | FLT3LTA4HKDM4E | |
| SCHEMBL1578671 | 0.76 | LTA4H (0.56) | MAOBACHELTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1577288-A1 | SELECTIVE ESTROGEN RECEPTOR MODULATORS | Eisai Co., Ltd. (JP) | 2005-09-21 | — | — | EP | disclosed |