Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.61 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.40 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | ABAT | P80404 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL725564 | 0.76 | SIGMAR1 (1.00) | SIGMAR1 | |
| Bromide SCHEMBL4392392 | 0.75 | SIGMAR1 (1.00) | SIGMAR1 | |
| SCHEMBL18606184 | 0.73 | SIGMAR1 (0.59) | SIGMAR1 | |
| SCHEMBL19380245 | 0.69 | TAAR1 (0.44) | SIGMAR1LOXL2 | |
| SCHEMBL12294725 | 0.69 | HRH3 (0.48) | LOXL2HRH3ABAT | |
| SCHEMBL28945126 | 0.67 | LOXL2 (0.39) | LOXL2HRH3ABAT | |
| SCHEMBL28945130 | 0.67 | SIGMAR1 (0.61) | SIGMAR1 | |
| SCHEMBL30239452 | 0.67 | LOXL2 (0.39) | LOXL2HRH3ABAT | |
| SCHEMBL3864241 | 0.66 | F10 (0.60) | — | |
| SCHEMBL112580 | 0.66 | ALDH1A1 (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1286673-B8 | LIGANDS OF INTEGRIN RECEPTORS | ABBOTT GMBH & CO KG (DE) | 2005-07-20 | — | — | EP | disclosed |
| EP-1286673-B1 | LIGANDS OF INTEGRIN RECEPTORS | BASF AG (DE) | 2005-05-25 | — | — | EP | disclosed |
| EP-1286673-A2 | LIGANDS OF INTEGRIN RECEPTORS | Basf Aktiengesellschaft (DE) | 2003-03-05 | — | — | EP | disclosed |
| WO-2001093840-A2 | LIGANDS OF INTEGRIN RECEPTORS | BASF AG (DE) | 2001-12-13 | — | — | WO | disclosed |