Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 5/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 4/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.32 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6426832 | 0.98 | PTGS2 (0.43) | PTGS2PTGS1AKR1C3AKR1C2S1PR3 | |
| SCHEMBL6458627 | 0.92 | PTGS2 (0.43) | PTGS2PTGS1AKR1C3AKR1C2GAA | |
| SCHEMBL6454261 | 0.90 | PTGS2 (0.43) | PTGS2PTGS1AKR1C3AKR1C2 | |
| SCHEMBL6423996 | 0.89 | USP30 (0.33) | PTGS2PTGS1AKR1C3AKR1C2USP30 | |
| SCHEMBL6425844 | 0.89 | PTGS2 (0.56) | PTGS2PTGS1AKR1C3AKR1C2MEN1 | |
| SCHEMBL6423294 | 0.89 | PTGS2 (0.56) | PTGS2PTGS1AKR1C3AKR1C2MEN1 | |
| SCHEMBL6427491 | 0.88 | AKR1C3 (0.41) | PTGS2PTGS1AKR1C3AKR1C2GAA | |
| SCHEMBL6425917 | 0.87 | MEN1 (0.33) | PTGS2PTGS1AKR1C3AKR1C2USP30 | |
| SCHEMBL6425442 | 0.87 | PTGS2 (0.45) | PTGS2PTGS1AKR1C3AKR1C2GAA | |
| SCHEMBL6425517 | 0.87 | PTGS2 (0.56) | PTGS2PTGS1AKR1C3AKR1C2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050234244-A1 | Synthesis of COX-2 and FAAH inhibitors | IRONWOOD PHARMACEUTICALS, INC. | 2005-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050234244-A1 | Synthesis of COX-2 and FAAH inhibitors | FAAH2, FAAH, PTGES2 | PTGS2 4/4885PTGS1 7/4885AKR1C3 577/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.