SCHEMBL6425318

SCHEMBL6425318

Cc1cc([Si](C)(C)C)c(C)cc1[Si](C)(C)C

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9742211 0.94 CYP3A4 (0.36) IDO1
SCHEMBL26191685 0.86 ACHE (0.31)
SCHEMBL12818366 0.86
SCHEMBL9628628 0.86 TSHR (0.33) IDO1
SCHEMBL27928678 0.84
SCHEMBL12817330 0.82
SCHEMBL12816949 0.82
SCHEMBL21277268 0.80 NOS3 (0.36)
SCHEMBL18234129 0.78 NOTUM (0.32)
SCHEMBL15829539 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5082959-A Oxidation of alkyl groups substituted on a trialkylsilyl-substituted aromatic ring using oxygen gas and a cobalt and/or manganese compound and a bromide as catalyts AMOCO CORPORATION (US) 1992-01-21 US claimed
US-6885038-B2 Light-emitting polymers and polymer light-emitting diodes AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2005-04-26 US disclosed
US-20030088043-A1 Light-emitting polymers and polymer light-emitting diodes AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2003-05-08 US disclosed
US-5082959-A Oxidation of alkyl groups substituted on a trialkylsilyl-substituted aromatic ring using oxygen gas and a cobalt and/or manganese compound and a bromide as catalyts AMOCO CORPORATION (US) 1992-01-21 US disclosed