Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5558576 | 1.00 | CA1 (0.36) | CA1CA2PTGS2PTGS1 | |
| SCHEMBL6426702 | 1.00 | CA1 (0.36) | CA1CA2PTGS2PTGS1 | |
| SCHEMBL6424964 | 0.90 | PTGS2 (0.39) | CA1CA2PTGS2PTGS1 | |
| SCHEMBL6424152 | 0.90 | PTGS2 (0.39) | CA1CA2PTGS2PTGS1 | |
| SCHEMBL6425008 | 0.90 | PTGS2 (0.39) | CA1CA2PTGS2PTGS1 | |
| SCHEMBL6425011 | 0.90 | PTGS2 (0.39) | CA1CA2PTGS2PTGS1 | |
| SCHEMBL6424154 | 0.90 | PTGS2 (0.39) | CA1CA2PTGS2PTGS1 | |
| SCHEMBL5560858 | 0.90 | PTGS2 (0.33) | CA1CA2PTGS2PTGS1 | |
| SCHEMBL6423242 | 0.89 | CA1 (0.30) | CA1CA2 | |
| SCHEMBL6425589 | 0.89 | CA1 (0.30) | CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050234244-A1 | Synthesis of COX-2 and FAAH inhibitors | IRONWOOD PHARMACEUTICALS, INC. | 2005-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050234244-A1 | Synthesis of COX-2 and FAAH inhibitors | FAAH2, FAAH, PTGES2 | CA1 960/4885CA2 1164/4885PTGS2 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.