Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | HPGD | P15428 | 5/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | JAK1 | P23458 | 1/20 | 0.42 |
| ▸ | TYK2 | P29597 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6426371 | 0.92 | RAB9A (0.42) | ALDH1A1L3MBTL1RAB9AHTTNPC1 | |
| SCHEMBL6427146 | 0.91 | JAK1 (0.45) | KDM4EALDH1A1HPGDMAPK10HSD17B10 | |
| SCHEMBL13927765 | 0.90 | ALDH1A1 (0.48) | KDM4EALDH1A1HPGDJAK1TYK2 | |
| SCHEMBL6427155 | 0.90 | ALDH1A1 (0.48) | KDM4EALDH1A1HPGDMAPK10HSD17B10 | |
| SCHEMBL6427309 | 0.89 | KDM4E (0.44) | KDM4EALDH1A1HPGDMAPK10HSD17B10 | |
| SCHEMBL4148835 | 0.88 | TP53 (0.46) | KDM4EALDH1A1HPGDKMT2AL3MBTL1 | |
| SCHEMBL4148832 | 0.88 | TP53 (0.46) | KDM4EALDH1A1HPGDKMT2AL3MBTL1 | |
| SCHEMBL4152208 | 0.87 | MAPT (0.45) | KDM4EKMT2AL3MBTL1LMNAPDE10A | |
| SCHEMBL4152203 | 0.87 | MAPT (0.45) | KDM4EKMT2AL3MBTL1LMNAPDE10A | |
| SCHEMBL4145935 | 0.86 | LMNA (0.42) | KDM4EALDH1A1HPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050261339-A1 | Pyrazole compound and medicinal composition containing the same | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2005-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050261339-A1 | Pyrazole compound and medicinal composition containing the same | CNKSR1, NR3C2, CSNK2B | KDM4E 2795/4885ALDH1A1 2713/4885HPGD 2100/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.