Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | PARP1 | P09874 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | KLKB1 | P03952 | 7/20 | 0.47 |
| ▸ | KLK1 | P06870 | 1/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | AADAT | Q8N5Z0 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL174972 | 0.89 | PARP1 (0.62) | ALDH1A1L3MBTL1PARP1KMT2AKLKB1 | |
| SCHEMBL16247044 | 0.84 | KLKB1 (0.58) | ALDH1A1L3MBTL1KMT2AKLKB1KDM4E | |
| SCHEMBL16246925 | 0.84 | KLKB1 (0.62) | KLKB1KLK1 | |
| SCHEMBL4544356 | 0.82 | ALDH1A1 (0.57) | ALDH1A1L3MBTL1KMT2AKLKB1ADORA2A | |
| SCHEMBL31058787 | 0.81 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1PARP1KMT2AKLKB1 | |
| SCHEMBL6052401 | 0.81 | ALDH1A1 (0.56) | ALDH1A1L3MBTL1PARP1KMT2AKLKB1 | |
| SCHEMBL16246898 | 0.81 | KLKB1 (0.57) | KLKB1 | |
| SCHEMBL4265334 | 0.79 | ALDH1A1 (0.78) | ALDH1A1L3MBTL1PARP1KMT2AKLKB1 | |
| SCHEMBL8756843 | 0.78 | ADORA2A (0.53) | ALDH1A1L3MBTL1PARP1KMT2AADORA2A | |
| SCHEMBL30730181 | 0.77 | DGAT1 (0.55) | ALDH1A1L3MBTL1PARP1KMT2AKLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10640486-B2 | Heteroarylcarboxamide derivatives as plasma kallikrein inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2020-05-05 | — | — | US | disclosed |
| CN-1960976-A | 4-carbox pyrazole derivates useful as anti-viral agents | SMITHKLINE BEECHAM CORP (US) | 2007-05-09 | — | — | CN | disclosed |
| EP-1592693-A1 | BENZAMIDE DERIVATIVES AS OXYTOCIN AGONISTS AND VASOPRESSIN ANTAGONISTS | Ferring B.V. (NL) | 2005-11-09 | — | — | EP | disclosed |
| WO-2004072083-A1 | BENZAMIDE DERIVATIVES AS OXYTOCIN AGONISTS AND VASOPRESSIN ANTAGONISTS | FERRING B.V. (NL) | 2004-08-26 | — | — | WO | disclosed |
| CN-1126753-C | Anticonvulsant and antiallergic/antiasthmatic pyrazolo [3, 4-d ] pyrimidines | DRESDEN ARZNEIMITTEL (DE) | 2003-11-05 | — | — | CN | disclosed |
| CN-1275128-A | Pyrazolo (3,4-D) pyrimidines with anticonvulsive and antialiergic/antiasthmatic action | DRESDEN ARZNEIMITTEL (DE) | 2000-11-29 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10640486-B2 | Heteroarylcarboxamide derivatives as plasma kallikrein inhibitors | KLKB1, BDKRB1, BDKRB2 | ALDH1A1 1597/4885L3MBTL1 489/4885PARP1 2395/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.