Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 2/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | DHODH | Q02127 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.55 |
| ▸ | FABP4 | P15090 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22191760 | 0.88 | KMT2A (0.76) | KMT2ASMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL28695522 | 0.87 | KMT2A (0.70) | KMT2ATDP1L3MBTL1SMN1; SMN2NPC1 | |
| SCHEMBL29740659 | 0.86 | KMT2A (0.79) | KMT2ATDP1L3MBTL1SMN1; SMN2NPC1 | |
| SCHEMBL1308673 | 0.85 | AKR1C2 (0.62) | KMT2ATDP1L3MBTL1SMN1; SMN2NPC1 | |
| SCHEMBL2058331 | 0.85 | ALDH1A1 (0.68) | KMT2ASMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL1308617 | 0.84 | PTPRC (0.59) | KMT2ATDP1L3MBTL1SMN1; SMN2NPC1 | |
| SCHEMBL1308303 | 0.83 | TP53 (0.78) | KMT2ASMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL1309907 | 0.83 | GRIK1 (0.71) | KMT2ASMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL1308455 | 0.82 | PTPN1 (0.60) | KMT2ATDP1L3MBTL1SMN1; SMN2NPC1 | |
| SCHEMBL358066 | 0.81 | KMT2A (0.72) | KMT2ATDP1L3MBTL1SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1212056-B1 | METHODS AND COMPOSITIONS FOR BISUBSTRATE INHIBITORS OF ACETYLTRANSFERASES | US GOV HEALTH & HUMAN SERV (US) | 2005-12-07 | — | — | EP | disclosed |