Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5498693 | 0.83 | MAPT (0.33) | LMNAMEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL6066242 | 0.80 | SLC6A1 (0.32) | LMNA | |
| SCHEMBL6386231 | 0.80 | CYP3A4 (0.36) | LMNAMEN1KMT2A | |
| SCHEMBL6426899 | 0.78 | MEN1 (0.31) | MEN1KMT2A | |
| SCHEMBL6065063 | 0.77 | MEN1 (0.30) | MEN1KMT2A | |
| SCHEMBL28760707 | 0.76 | MEN1 (0.35) | LMNAMEN1KMT2AMAPT | |
| SCHEMBL28755600 | 0.73 | NTRK1 (0.39) | LMNAMEN1KMT2AMAPT | |
| SCHEMBL5500962 | 0.72 | ADRA2C (0.39) | — | |
| SCHEMBL3116816 | 0.72 | GAA (0.35) | LMNAMEN1KMT2A | |
| SCHEMBL6065815 | 0.71 | LPAR1 (0.33) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1556389-A1 | CEPHEM COMPOUNDS | Astellas Pharma Inc. (JP) | 2005-07-27 | — | — | EP | disclosed |
| WO-2004039814-A1 | CEPHEM COMPOUNDS | ASTELLAS PHARMA INC. (JP) | 2004-05-13 | — | — | WO | disclosed |