Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | VDR | P11473 | 3/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CASP6 | P55212 | 1/20 | 0.33 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | IGF1R | P08069 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5569437 | 0.83 | BACE1 (0.60) | BACE1BCHEESR1CYP19A1ESR2 | |
| SCHEMBL18199330 | 0.80 | TYR (0.48) | VDRESR1HSD17B10KDM4EALOX15 | |
| SCHEMBL28154532 | 0.77 | PTGS2 (0.53) | ESR1HSD17B10KDM4EKAT8PPARA | |
| SCHEMBL10415499 | 0.77 | KAT8 (0.49) | ESR1HSD17B10KDM4EKAT8PPARA | |
| SCHEMBL11010604 | 0.77 | CNR1 (0.47) | BACE1VDR | |
| SCHEMBL13953779 | 0.76 | CNR1 (0.50) | BACE1VDRALOX15 | |
| SCHEMBL8770880 | 0.76 | TRPA1 (0.48) | BACE1VDRCYP1A2AKT1 | |
| SCHEMBL20657270 | 0.75 | TYR (0.47) | VDRBCHEESR1HSD17B10KDM4E | |
| SCHEMBL5570212 | 0.75 | TYR (0.34) | BACE1VDRBCHEESR1CYP19A1 | |
| SCHEMBL5565041 | 0.74 | PTGDR2 (0.51) | PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1537065-A1 | ANALOGUES OF VITAMIN D | Galderma Research & Development, S.N.C. (FR) | 2005-06-08 | — | — | EP | disclosed |
| WO-2004020379-A1 | ANALOGUES OF VITAMIN D | GALDERMA RESEARCH & DEVELOPMENT, SNC (FR) | 2004-03-11 | — | — | WO | disclosed |