Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.62 |
| ▸ | HTT | P42858 | 3/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.55 |
| ▸ | HPGD | P15428 | 5/20 | 0.55 |
| ▸ | ESR1 | P03372 | 1/20 | 0.53 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.53 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.53 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | GGT1 | P19440 | 1/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28259939 | 0.98 | ALDH1A1 (0.62) | ALDH1A1KMT2APTK2BKDM4EHTT | |
| SCHEMBL18700963 | 0.85 | ALDH1A1 (0.71) | ALDH1A1KMT2APTK2BKDM4EHTT | |
| SCHEMBL31133329 | 0.85 | ALDH1A1 (0.71) | ALDH1A1KMT2APTK2BKDM4EHTT | |
| SCHEMBL11023511 | 0.84 | ALDH1A1 (0.46) | ALDH1A1KMT2APTK2BKDM4EHTT | |
| SCHEMBL633198 | 0.83 | ALDH1A1 (0.69) | ALDH1A1KMT2APTK2BKDM4EHTT | |
| SCHEMBL29444034 | 0.83 | ALDH1A1 (0.69) | ALDH1A1KMT2APTK2BKDM4EHTT | |
| SCHEMBL30211332 | 0.83 | ALDH1A1 (0.89) | ALDH1A1KMT2APTK2BKDM4EHTT | |
| SCHEMBL2049483 | 0.83 | ALDH1A1 (0.89) | ALDH1A1KMT2APTK2BKDM4EHTT | |
| SCHEMBL10937345 | 0.83 | DRD2 (0.56) | ALDH1A1KMT2APTK2BMAPTRAB9A | |
| SCHEMBL18700982 | 0.83 | FABP3 (0.50) | ALDH1A1KMT2APTK2BKDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106365978-B | A kind of preparation method of the fluoro- 6- methoxy benzoic acid of 2,3- bis- | 绍兴上虞华伦化工有限公司 | 2019-01-11 | — | — | CN | claimed |
| EP-3359620-B1 | METHOD OF MONITORING A PARAMETER OF A HYDROCARBON WELL, PIPELINE OR FORMATION | JOHNSON MATTHEY PLC (GB) | 2022-11-30 | — | — | EP | disclosed |
| CN-110520127-A | Piperidinyl-substituted and piperazinyl-substituted heteroaromatic carboxamides as modulators of GPR6 | TAKEDA PHARMACEUTICALS CO | 2019-11-29 | — | — | CN | disclosed |
| US-10365262-B2 | Method of monitoring a parameter of a hydrocarbon well, pipeline or formation | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 2019-07-30 | — | — | US | disclosed |
| CN-106164047-B | 1,2- substituted cyclopentane as orexin receptor antagonists | 武田药品工业株式会社 | 2019-04-16 | — | — | CN | disclosed |
| CN-109641854-A | Integration stress access regulator | 卡里科生命科学有限责任公司 | 2019-04-16 | — | — | CN | disclosed |
| CN-106365978-B | A kind of preparation method of the fluoro- 6- methoxy benzoic acid of 2,3- bis- | 绍兴上虞华伦化工有限公司 | 2019-01-11 | — | — | CN | disclosed |
| CN-106365978-B | A kind of preparation method of the fluoro- 6- methoxy benzoic acid of 2,3- bis- | 绍兴上虞华伦化工有限公司 | 2019-01-11 | — | — | CN | disclosed |
| CN-106365978-B | A kind of preparation method of the fluoro- 6- methoxy benzoic acid of 2,3- bis- | 绍兴上虞华伦化工有限公司 | 2019-01-11 | — | — | CN | disclosed |
| US-20180284096-A1 | METHOD OF MONITORING A PARAMETER OF A HYDROCARBON WELL, PIPELINE OR FORMATION | TRACERCO LIMITED (GB) | 2018-10-04 | — | — | US | disclosed |
| WO-2017060702-A1 | METHOD OF MONITORING A PARAMETER OF A HYDROCARBON WELL, PIPELINE OR FORMATION | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 2017-04-13 | — | — | WO | disclosed |
| US-9102665-B2 | Cysteinyl leukotriene antagonists | SUN PHARMA ADVANCED RESEARCH COMPANY LTD. (IN) | 2015-08-11 | — | — | US | disclosed |
| US-20140155596-A1 | CYSTEINYL LEUKOTRIENE ANTAGONISTS | SUN PHARMA ADVANCED RESEARCH COMPANY LTD. (IN) | 2014-06-05 | — | — | US | disclosed |
| EP-1606261-A1 | NOVEL PROCESS FOR THE PREPARATION OF ROFLUMILAST | ALTANA Pharma AG (DE) | 2005-12-21 | — | — | EP | disclosed |
| EP-1553929-A2 | CONTROLLED RELEASE PREPARATION | Takeda Pharmaceutical Company Limited (JP) | 2005-07-20 | — | — | EP | disclosed |
| WO-2004080967-A1 | NOVEL PROCESS FOR THE PREPARATION OF ROFLUMILAST | ALTANA PHARMA AG (DE) | 2004-09-23 | — | — | WO | disclosed |
| WO-2004035020-A2 | CONTROLLED RELEASE PREPARATION | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-04-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140155596-A1 | CYSTEINYL LEUKOTRIENE ANTAGONISTS | LTC4S, CYSLTR2, CYSLTR1 | ALDH1A1 2177/4885KMT2A 3738/4885PTK2B 2182/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.