Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.60 |
| ▸ | PLK1 | P53350 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | HRH2 | P25021 | 1/20 | 0.54 |
| ▸ | HRH1 | P35367 | 1/20 | 0.54 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | CES2 | O00748 | 1/20 | 0.52 |
| ▸ | CES1 | P23141 | 1/20 | 0.52 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.51 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1814631 | 0.93 | MAPT (0.62) | MAPTL3MBTL1LMNAMEN1MAPK1 | |
| SCHEMBL6341040 | 0.93 | L3MBTL1 (0.68) | MAPTL3MBTL1PLK1LMNAMAPK1 | |
| SCHEMBL11578668 | 0.87 | KMT2A (0.67) | MAPTL3MBTL1PLK1LMNAMAPK1 | |
| SCHEMBL11577173 | 0.86 | MTNR1B (0.61) | MAPTL3MBTL1LMNAMEN1MAPK1 | |
| SCHEMBL13845292 | 0.86 | LTA4H (0.68) | MAPTL3MBTL1PLK1LMNAMAPK1 | |
| SCHEMBL10426837 | 0.86 | MAPT (0.62) | MAPTL3MBTL1LMNAMEN1MAPK1 | |
| SCHEMBL50488 | 0.86 | GAA (0.72) | MAPTL3MBTL1PLK1LMNAMEN1 | |
| SCHEMBL719973 | 0.86 | GAA (0.72) | MAPTL3MBTL1LMNAMEN1MAPK1 | |
| SCHEMBL11576081 | 0.85 | KMT2A (0.69) | MAPTL3MBTL1PLK1LMNAMEN1 | |
| SCHEMBL8769969 | 0.85 | TP53 (0.68) | L3MBTL1MEN1KMT2AHPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0954522-B1 | NOVEL SUBSTITUTED NAPHTHOPYRANS | TRANSITIONS OPTICAL INC (US) | 2005-10-12 | — | — | EP | disclosed |
| US-5651923-A | PHOTOCHROMIC ARTICLE | TRANSITIONS OPTICAL, INC. (US) | 1997-07-29 | — | — | US | disclosed |